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How to get fromKey West to Winston-Salemby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Winston-Salem

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There are 7 ways to get from Key West to Winston-Salem by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Key West International Airport (EYW) to Piedmont Triad International Airport (GSO)plane plane EYW - GSO
    5h 17m
    $111–457

  2. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Fayetteville Bus Stationbus bus
    4. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus
    27h 17m
    $171–269

  3. Bus, train via Fayetteville

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Hollywood Amtrak Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus
    29h 3m
    $504–785

  4. Drive  959.9 mi

    1. Drive from Key West to Winston-Salemcar car 959.9 mi
    16h 45m
    $176–253

  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Key West International Airport (EYW) to Charlotte Douglas International Airport (CLT)plane plane EYW - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    5h 39m
    $149–691

  6. Fly to Raleigh-Durham International Airport, bus

    1. Fly from Key West International Airport (EYW) to Raleigh-Durham International Airport (RDU)plane plane EYW - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    6h 42m
    $132–642

  7. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Hollywood Amtrak Station to Carytrain train
    4. Take the train from Cary to Greensborotrain train
    5. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    32h 25m
    $572–968

Key West to Winston-Salem by bus and foot

Calendar4Weekly Services
Duration27h 17mAverage Duration
Ticket$171Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to Winston-Salem.ExpandLaunch map view
  • Distance: 830.7 mi
  • Duration: 5h 17m

What companies run services between Key West, FL, USA and Winston-Salem, NC, USA?

American Airlines and Delta fly from Key West International Airport (EYW) to Piedmont Triad International Airport (GSO) every 2 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Winston Salem(Trans Center) via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Fayetteville Bus Station in around 27h 17m.

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