There are 7 ways to get from Kirksville to Cape Girardeau by train, bus, car, plane, taxi, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from La Plata Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg Amtrak Station to Springfieldbus
- Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Cape Girardeaubus
12h 3m$162–272Shuttle, bus
cheapest- Take a shuttle bus from Hy-Vee - Kirksville to Columbia
- Take a shuttle bus from Columbia to Bowling Green, Mo
- Take a shuttle bus from Bowling Green, Mo to St. Louis
- Take the bus from St Louis Bus Station to Cape Girardeaubus
9h 45m$38–65Train, bus via Kansas City
- Take the train from La Plata Station to Kansas Citytrain
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Cape Girardeaubus
12h 36m$195–384Drive 304.3 mi
- Drive from Kirksville to Cape Girardeaucar 304.3 mi
5h 26m$56–81Fly Kirksville Regional Airport to Cape Girardeau Municipal Airport
- Fly from Kirksville Regional Airport (IRK) to Cape Girardeau Municipal Airport (CGI)plane IRK - CGI
25h 5m$229–721Fly Kirksville Regional Airport to Williamson County Regional Airport, taxi
- Fly from Kirksville Regional Airport (IRK) to Williamson County Regional Airport (MWA)plane IRK - MWA
- Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi
9h 29m$326–803Drive to Burlington Municipal Airport, fly to Cape Girardeau Municipal Airport
- Drive from Kirksville to Burlington Municipal Airport (BRL)car
- Fly from Burlington Municipal Airport (BRL) to Cape Girardeau Municipal Airport (CGI)plane BRL - CGI
14h 26m$174–609
Kirksville Regional Airport (IRK) to Cape Girardeau Municipal Airport (CGI) flights
Questions & Answers
The cheapest way to get from Kirksville to Cape Girardeau is to shuttle and bus which costs $35 - $65 and takes 9h 45m.
The fastest way to get from Kirksville to Cape Girardeau is to drive which takes 5h 26m and costs $55 - $80.
The distance between Kirksville and Cape Girardeau is 483 miles. The road distance is 306.1 miles.
The best way to get from Kirksville to Cape Girardeau without a car is to train and bus which takes 12h 3m and costs $160 - $280.
It takes approximately 12h 3m to get from Kirksville to Cape Girardeau, including transfers.
Yes, the driving distance between Kirksville to Cape Girardeau is 306 miles. It takes approximately 5h 26m to drive from Kirksville to Cape Girardeau.
There are 17+ hotels available in Cape Girardeau.
What companies run services between Kirksville, MO, USA and Cape Girardeau, MO, USA?
Corporate Flight Management Inc flies from Kirksville Regional Airport (IRK) to Cape Girardeau Municipal Airport (CGI) twice daily.
- Website
- contouraviation.com
Flights from Kirksville Regional Airport to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 24h 40m
- When
- Every day
- Estimated price
- $170–650
Flights from Kirksville Regional Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 27h 25m
- When
- Monday, Wednesday, Thursday, and Sunday
- Estimated price
- $270–1,000
Flights from Kirksville Regional Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 8h 5m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–600
Flights from Burlington Municipal Airport to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 21h 10m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–600
Flights from Burlington Municipal Airport to Cape Girardeau Municipal Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 11h 25m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $130–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Plata Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Amtrak
Train from La Plata Station to Kansas City
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- $40–95
- Website
- Amtrak
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $85–190
- Website
- Amtrak
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Galesburg Amtrak Station to Springfield
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Springfield SMTD Transfer Center to St Louis Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $15–26
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
- Phone
- +1-888-875-6287
- Website
- Oats Transit
Shuttle from Hy-Vee - Kirksville to Columbia
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $4–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
Shuttle from Columbia to Bowling Green, Mo
- Ave. Duration
- 1h 44m
- Frequency
- On demand
- Estimated price
- $4–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
Shuttle from Bowling Green, Mo to St. Louis
- Ave. Duration
- 1h 16m
- Frequency
- Twice a week
- Estimated price
- $3–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
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