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How to get fromKirksville to Indianapolisby train, bus, train (Amtrak), car, or plane

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There are 11 ways to get from Kirksville to Indianapolis by train, bus, train (Amtrak), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from La Plata Station to Galesburg Amtrak Stationtrain train Southwest Chief
    2. Take the bus from Galesburg to Indianapolisbus bus Btw 1402
    8h 33m

  2. Drive 387.7 mi

    cheapest
    1. Drive from Kirksville to Indianapoliscar car 387.7 mi
    7h 10m
    $71–103

  3. Train (Amtrak)

    1. Take the train from La Plata Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    11h 48m
    $201–385

  4. Fly Kirksville Regional Airport to Indianapolis

    1. Fly from Kirksville Regional Airport (IRK) to Indianapolis (IND)plane plane IRK - IND
    5h 58m
    $228–795

  5. Train, bus via Galesburg

    1. Take the train from La Plata Station to Galesburg Amtrak Stationtrain train Southwest Chief
    2. Take the bus from Galesburg to Indianapolis Union Stationbus bus Greyhound US0157S
    8h 43m
    $121–220

  6. Train to Kansas City, fly to Indianapolis

    1. Take the train from La Plata Station to Kansas Citytrain train
    2. Fly from Kansas City (MCI) to Indianapolis (IND)plane plane MCI - IND
    8h 16m
    $743–1,152

  7. Fly Kirksville Regional Airport to Chicago O'Hare International Airport, train

    1. Fly from Kirksville Regional Airport (IRK) to Chicago O'Hare International Airport (ORD)plane plane IRK - ORD
    2. Take the train from Chicago Union Station to Indianapolistrain train
    8h 45m
    $163–368

  8. Train to Chicago O'Hare International Airport, fly to Indianapolis

    1. Take the train from La Plata Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Indianapolis (IND)plane plane ORD - IND
    10h 11m
    $565–1,562

  9. Train to Chicago Midway International Airport, fly to Indianapolis

    1. Take the train from La Plata Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Indianapolis (IND)plane plane MDW - IND
    9h 53m
    $213–755

  10. Drive to Burlington Municipal Airport, fly to Indianapolis

    1. Drive from Kirksville to Burlington Municipal Airport (BRL)car car
    2. Fly from Burlington Municipal Airport (BRL) to Indianapolis (IND)plane plane BRL - IND
    8h 46m
    $123–583

  11. Fly Kirksville Regional Airport to Purdue University Airport, train

    1. Fly from Kirksville Regional Airport (IRK) to Purdue University Airport (LAF)plane plane IRK - LAF
    2. Take the train from Lafayette Amtrak Station to Indianapolistrain train
    10h 2m
    $181–554

Kirksville Regional Airport (IRK) to Indianapolis (IND) flights

Calendar26Weekly Planes
Duration5h 45mAverage Duration
Ticket$169Cheapest Price
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Questions & Answers

Map of how to get from Kirksville to Indianapolis.ExpandLaunch map view
  • Distance: 403.9 mi
  • Duration: 8h 33m

What companies run services between Kirksville, MO, USA and Indianapolis, IN, USA?

You can take a vehicle from Kirksville to Indianapolis via La Plata Station and Chicago Union Station in around 11h 48m. Alternatively, Corporate Flight Management Inc, United Airlines, and American Airlines fly from Kirksville Regional Airport (IRK) to Indianapolis (IND) 4 times a day.

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Bus operators

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