There are 4 ways to get from Kirksville to Manhattan by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from La Plata Station to Kansas Citytrain Southwest Chief
- Take the bus from Kansas City Bus Station to Manhattan KSbus Greyhound US0180s
7h 59m$103–182Drive 264.3 mi
cheapest- Drive from Kirksville to Manhattancar 264.3 mi
5h 37m$49–70Fly
- Fly from Kirksville Regional Airport (IRK) to Manhattan Regional Airport (MHK)plane IRK - MHK
4h 59m$127–474Train, bus via Lawrence
- Take the train from La Plata Station to Kansas Citytrain
- Take the bus from Kansas City Bus Station to Lawrence Bus Stopbus
- Take the bus from Lawrence Bus Stop to Manhattan KSbus
7h 59m$98–173
Kirksville Regional Airport (IRK) to Manhattan Regional Airport (MHK) flights
Questions & Answers
The cheapest way to get from Kirksville to Manhattan is to drive which costs $45 - $70 and takes 5h 37m.
The fastest way to get from Kirksville to Manhattan is to fly which takes 4h 59m and costs $120 - $480.
The distance between Kirksville and Manhattan is 311 miles. The road distance is 265.8 miles.
The best way to get from Kirksville to Manhattan without a car is to train and bus which takes 7h 59m and costs $100 - $190.
It takes approximately 7h 59m to get from Kirksville to Manhattan, including transfers.
Yes, the driving distance between Kirksville to Manhattan is 266 miles. It takes approximately 5h 37m to drive from Kirksville to Manhattan.
There are 28+ hotels available in Manhattan.
What companies run services between Kirksville, MO, USA and Manhattan, KS, USA?
Corporate Flight Management Inc and American Airlines fly from Kirksville Regional Airport (IRK) to Manhattan Regional Airport (MHK) twice daily.
- Website
- aa.com
Flights from Kirksville Regional Airport to Manhattan Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $75–410
Flights from Kirksville Regional Airport to Manhattan Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 49m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–900
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Plata Station to Kansas City
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Amtrak
Train from La Plata Station to Kansas City
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Kansas City Bus Station to Manhattan KS
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $23–45
- Website
- Greyhound
Bus from Kansas City Bus Station to Lawrence Bus Stop
- Ave. Duration
- 45 min
- Frequency
- 3 times a day
- Estimated price
- $6–12
- Website
- Greyhound
Bus from Lawrence Bus Stop to Manhattan KS
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $12–24
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Kansas City Bus Station to Lawrence Bus Stop
- Ave. Duration
- 45 min
- Frequency
- 6 times a week
- Estimated price
- $6–11
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide









