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How to get fromKirksville to Mayo Clinicby car, bus, plane, train, or shuttle

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There are 6 ways to get from Kirksville to Mayo Clinic by car, bus, plane, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus

    best
    1. Drive from Kirksville to Ottumwa Bus Stopcar car
    2. Take the bus from Ottumwa Bus Stop to Des Moinesbus bus
    3. Take the bus from Des Moines to Saint Paul Union Depotbus bus
    4. Take the bus from St. Paul to Rochesterbus bus
    12h 22m
    $88–152

  2. Drive 289.7 mi

    cheapest
    1. Drive from Kirksville to Mayo Cliniccar car 289.7 mi
    6h 19m
    $53–77

  3. Drive to The Eastern Iowa Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Kirksville to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Minneapolis–Saint Paul International Airport (MSP)plane plane CID - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 35m
    $181–794

  4. Train, bus, shuttle

    1. Take the train from La Plata Station to Kansas Citytrain train
    2. Take the bus from Kansas City to Owatonnabus bus
    3. Take a shuttle bus from Owatonna, MN to Rochestershuttle bus
    13h 49m
    $181–320

  5. Train, bus

    1. Take the train from La Plata Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    16h
    $211–385

  6. Fly Kirksville Regional Airport to Rochester

    1. Fly from Kirksville Regional Airport (IRK) to Rochester (RST)plane plane IRK - RST
    8h 13m
    $107–463

The Eastern Iowa Airport (CID) to Minneapolis–Saint Paul International Airport (MSP) flights

Calendar21Weekly Planes
Duration1h 16mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

Map of how to get from Kirksville to Mayo Clinic.ExpandLaunch map view
  • Distance: 470 mi
  • Duration: 12h 22m

What companies run services between Kirksville, MO, USA and Mayo Clinic, MN, USA?

Corporate Flight Management Inc, American Airlines, and Delta fly from Kirksville Regional Airport (IRK) to Rochester (RST) 3 times a day.

Airlines
Train operators
Bus operators

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