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How to get fromKirksville to Saint Charlesby train (Amtrak), train, bus, car, or shuttle

Find Transport to Saint Charles

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There are 4 ways to get from Kirksville to Saint Charles by train (Amtrak), train, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Plata Station to Kansas Citytrain train Southwest Chief
    2. Take the train from Kansas City to St. Louistrain train Missouri River Runner / ...
    10h 52m
    $180–344
  2. Shuttle

    cheapest
    1. Take a shuttle bus from Hy-Vee - Kirksville to Columbiashuttle bus
    2. Take a shuttle bus from Columbia to Bowling Green, Moshuttle bus
    3. Take a shuttle bus from Bowling Green, Mo to St. Louisshuttle bus
    6h 49m
    $12–19
  3. Train, bus

    1. Take the train from La Plata Station to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus bus
    10h 53m
    $140–231
  4. Drive 185.9 mi

    1. Drive from Kirksville to Saint Charlescar car 185.9 mi
    3h 25m
    $34–49

Questions & Answers

What companies run services between Kirksville, MO, USA and Saint Charles, MO, USA?

You can take a vehicle from Kirksville to 4375 Rider Trail North Sb via La Plata Station, Kansas City, St. Louis, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 10h 52m. Alternatively, you can take a shuttle from Hy-Vee - Kirksville to 4375 Rider Trail North Sb via Columbia, Bowling Green, Mo, St. Louis, and North Hanley Transit Center in around 6h 49m.

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