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How to get fromKirksville to St. Louis (Region)by train, bus, train (Amtrak), car, or shuttle

Find Transport to St. Louis (Region)

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There are 4 ways to get from Kirksville to St. Louis (Region) by train, bus, train (Amtrak), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from La Plata Station to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus bus
    8h 59m
    $139–234

  2. Shuttle

    cheapest
    1. Take a shuttle bus from Hy-Vee - Kirksville to Columbiashuttle bus
    2. Take a shuttle bus from Columbia to Bowling Green, Moshuttle bus
    3. Take a shuttle bus from Bowling Green, Mo to St. Louisshuttle bus
    6h 16m
    $37–49

  3. Train (Amtrak)

    1. Take the train from La Plata Station to Kansas Citytrain train Southwest Chief
    2. Take the train from Kansas City to St. Louistrain train Missouri River Runner / ...
    9h 27m
    $181–340

  4. Drive 205.6 mi

    1. Drive from Kirksville to St. Louis (Region)car car 205.6 mi
    3h 45m
    $38–55

Questions & Answers

Map of how to get from Kirksville to St. Louis (Region).ExpandLaunch map view
  • Distance: 364.7 mi
  • Duration: 8h 59m

What companies run services between Kirksville, MO, USA and St. Louis (Region), MO, USA?

You can take a vehicle from Kirksville to St. Louis via La Plata Station and Kansas City in around 9h 27m. Alternatively, you can take a shuttle from Hy-Vee - Kirksville to St. Louis (Region) via Columbia, Bowling Green, Mo, and St. Louis in around 6h 16m.

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Bus operators

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