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How to get fromKirksville to West Lafayetteby train, bus, car, plane, or train (Amtrak)

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There are 8 ways to get from Kirksville to West Lafayette by train, bus, car, plane, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from La Plata Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the bus from Chicago Bus Station to Lafayette Bus Stopbus bus FlixBus 2511 / ...
    8h 59m
    $154–290

  2. Drive 360.1 mi

    cheapest
    1. Drive from Kirksville to West Lafayettecar car 360.1 mi
    6h 46m
    $66–95

  3. Train, bus via Galesburg

    1. Take the train from La Plata Station to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Lafayette Bus Stopbus bus
    11h 18m
    $130–239

  4. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Kirksville Regional Airport (IRK) to Chicago O'Hare International Airport (ORD)plane plane IRK - ORD
    2. Take the bus from Chicago Bus Station to Lafayette Bus Stopbus bus
    5h 49m
    $121–273

  5. Train, bus #2 (Amtrak)

    1. Take the train from La Plata Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus Chicago
    9h 24m
    $159–300

  6. Train (Amtrak)

    1. Take the train from La Plata Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train Cardinal
    9h 55m
    $171–335

  7. Fly to Purdue University Airport

    1. Fly from Kirksville Regional Airport (IRK) to Purdue University Airport (LAF)plane plane IRK - LAF
    7h 3m
    $157–504

  8. Fly to Indianapolis, bus

    1. Fly from Kirksville Regional Airport (IRK) to Indianapolis (IND)plane plane IRK - IND
    2. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    7h 7m
    $264–833

Kirksville Regional Airport (IRK) to Chicago O'Hare International Airport (ORD) flights

Calendar7Weekly Planes
Duration1h 40mAverage Duration
Ticket$68Cheapest Price
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Questions & Answers

Map of how to get from Kirksville to West Lafayette.ExpandLaunch map view
  • Distance: 431 mi
  • Duration: 8h 59m

What companies run services between Kirksville, MO, USA and West Lafayette, IN, USA?

You can take a vehicle from Kirksville to Lafayette Amtrak Station via La Plata Station and Chicago Union Station in around 9h 55m. Alternatively, Corporate Flight Management Inc and United Airlines fly from Kirksville Regional Airport (IRK) to Purdue University Airport (LAF) once daily.

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