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How to get fromKissimmee to Des Moinesby plane, bus (Flixbus, Greyhound), train, bus, car, or taxi

Find Transport to Des Moines

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There are 5 ways to get from Kissimmee to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Orlando

    best
    1. Fly from Orlando (MCO) to Des Moines (DSM)plane plane MCO - DSM
    6h 42m
    $181–776
  2. Bus

    1. Take the bus from Orlando to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    34h 46m
    $217–412
  3. Train, bus

    1. Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    47h 14m
    $504–1,101
  4. Drive  1,330.4 mi

    1. Drive from Kissimmee to Des Moinescar car 1,330.4 mi
    23h 5m
    $243–351
  5. Taxi to Orlando Sanford, fly

    1. Take the taxi from Kissimmee to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    4h 4m
    $294–997

Kissimmee to Des Moines by bus

Calendar6Weekly Buses
Duration34h 46mAverage Duration
Ticket$217Cheapest Price
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Questions & Answers

What companies run services between Kissimmee, FL, USA and Des Moines, IA, USA?

Delta, Southwest Airlines, and two other airlines fly from Orlando (MCO) to Des Moines (DSM) hourly. Alternatively, you can take a bus from N Main St & E Cypress St to Des Moines via Florida Mall, Orlando, Atlanta Bus Station, and Indianapolis Union Station in around 34h 46m.

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