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How to get fromKissimmee to Florenceby plane, train (Amtrak), bus (Flixbus), or car

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There are 4 ways to get from Kissimmee to Florence by plane, train (Amtrak), bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Orlando (MCO) to Florence Regional Airport (FLO)plane plane MCO - FLO
    6h 2m
    $74–348
  2. Train (Amtrak)

    1. Take the train from Kissimmee Amtrak Station to Florence Stationtrain train Silver Meteor
    10h 25m
    $160–340
  3. Bus (Flixbus)

    1. Take the bus from Orlando Bus Station to Florencebus bus FlixBus N2472
    11h 8m
    $92–150
  4. Drive 463.5 mi

    1. Drive from Kissimmee to Florencecar car 463.5 mi
    7h 45m
    $85–123

Kissimmee to Florence by train (Amtrak)

Calendar7Weekly Trains
Duration10h 25mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

What companies run services between Kissimmee, FL, USA and Florence, SC, USA?

American Airlines and Frontier Airlines fly from Orlando (MCO) to Florence Regional Airport (FLO) 3 times a day. Alternatively, Amtrak operates a train from Kissimmee Amtrak Station to Florence Station once daily. Tickets cost $160–340 and the journey takes 10h 25m.

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