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How to get fromKissimmee to Florida Keysby plane, bus, train, bus (Flixbus, Greyhound), car, taxi, or shuttle

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There are 10 ways to get from Kissimmee to Florida Keys by plane, bus, train, bus (Flixbus, Greyhound), car, taxi, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Key West International Airport, bus

    best
    1. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    2. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    5h 52m
    $146–749

  2. Bus

    cheapest
    1. Take the bus from Orlando to Miami Airport Stationbus bus FlixBus 2411 / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    12h 6m
    $59–106

  3. Train, bus

    1. Take the train from Kissimmee Amtrak Station to Hollywood Amtrak Stationtrain train Silver Meteor / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    11h 57m
    $102–203

  4. Drive 340.8 mi

    1. Drive from Kissimmee to Florida Keyscar car 340.8 mi
    7h 5m
    $63–90

  5. Taxi to Orlando Sanford, fly to Key West International Airport

    1. Take the taxi from Kissimmee to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    5h 7m
    $219–470

  6. Fly Orlando to Miami International Airport, shuttle

    1. Fly from Orlando (MCO) to Miami International Airport (MIA)plane plane MCO - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    8h 26m
    $756–1,289

  7. Train to Tampa, fly to Key West International Airport

    1. Take the train from Kissimmee Amtrak Station to Tampatrain train
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    8h 10m
    $177–540

  8. Fly Orlando to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Orlando (MCO) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MCO - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    8h 53m
    $426–809

  9. Bus, shuttle

    1. Take the bus from Kissimmee -1471 East Osceola Parkway to Bayside Marketplacebus bus Orlando to Miami
    2. Take a shuttle bus from Bayside Marketplace to Plaza Hotelshuttle bus
    12h 22m
    $99–111

  10. Bus, train

    1. Take the bus from Kissimmee -1471 East Osceola Parkway to West Palm Beach, FLbus bus
    2. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    12h 26m
    $64–132

Kissimmee to Florida Keys by train, bus, and foot

Calendar14Weekly Services
Duration11h 57mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

Map of how to get from Kissimmee to Florida Keys.ExpandLaunch map view
  • Distance: 319.2 mi
  • Duration: 5h 52m

What companies run services between Kissimmee, FL, USA and Florida Keys, FL, USA?

You can take a bus from N Main St & E Cypress St to Florida Keys via Florida Mall, Orlando, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 12h 6m.

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