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How to get fromKissimmee to Florida Keysby taxi, plane, car, or train

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There are 4 ways to get from Kissimmee to Florida Keys by taxi, plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Orlando Sanford, fly

    best
    1. Take the taxi from Kissimmee to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    2h 18m
    $142–376

  2. Drive 356.3 mi

    cheapest
    1. Drive from Kissimmee to Key Westcar car 356.3 mi
    7h 28m
    $65–94

  3. Fly from Orlando

    1. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    3h 1m
    $74–655

  4. Train to Tampa, fly

    1. Take the train from Kissimmee Amtrak Station to Tampatrain train
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    5h 18m
    $100–446

Orlando Sanford (SFB) to Key West International Airport (EYW) flights

Calendar3Weekly Planes
Duration1h 20mAverage Duration
Ticket$39Cheapest Price
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Questions & Answers

Map of how to get from Kissimmee to Florida Keys.ExpandLaunch map view
  • Distance: 331.7 mi
  • Duration: 2h 18m

What companies run services between Kissimmee, FL, USA and Florida Keys, Monroe County, FL, USA?

Breeze Airways flies from Orlando (MCO) to Key West International Airport (EYW) 4 times a week.

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