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How to get fromKissimmee to Key West (Island)by plane, bus (Flixbus, Greyhound), train, bus, car, taxi, bus (Greyhound), or shuttle

Find Transport to Key West (Island)

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There are 8 ways to get from Kissimmee to Key West (Island) by plane, bus (Flixbus, Greyhound), train, bus, car, taxi, bus (Greyhound), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Orlando

    best
    1. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    3h 8m
    $69–705

  2. Drive  356.3 mi

    cheapest
    1. Drive from Kissimmee to Key Westcar car 356.3 mi
    7h 28m
    $63–91

  3. Bus

    1. Take the bus from Orlando to Miami Airport Stationbus bus FlixBus 2411 / ...
    2. Take the bus from Miami Airport Station to Key West Airportbus bus Greyhound US0720s
    10h 56m
    $65–102

  4. Train, bus

    1. Take the train from Kissimmee Amtrak Station to Hollywood Amtrak Stationtrain train Silver Meteor / ...
    2. Take the bus from Miami Airport Station to Key West Airportbus bus Greyhound US0720s
    11h 17m
    $159–248

  5. Taxi to Orlando Sanford, fly

    1. Take the taxi from Kissimmee to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    2h 18m
    $142–366

  6. Train to Tampa, fly

    1. Take the train from Kissimmee Amtrak Station to Tampatrain train
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    5h 15m
    $92–240

  7. Bus via Pembroke Pines

    1. Take the bus from Kissimmee -1471 East Osceola Parkway to Sheridan Tri-Rail Stationbus bus Orlando to Miami
    2. Take the bus from Miami Airport Station to Key West Airportbus bus Greyhound US0720s
    11h 17m
    $63–98

  8. Bus, shuttle

    1. Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus bus Tallahassee
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus To the Keys
    11h 35m
    $227–282

Kissimmee to Key West (Island) by bus

Calendar19Weekly Buses
Duration10h 56mAverage Duration
Ticket$65Cheapest Price
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Comparing Your Travel Options

Map of how to get from Kissimmee to Key West (Island).ExpandLaunch map view
  • Distance: 298 mi
  • Duration: 3h 8m

What companies run services between Kissimmee, FL, USA and Key West (Island), FL, USA?

Breeze Airways and American Airlines fly from Orlando (MCO) to Key West International Airport (EYW) twice daily. Alternatively, you can take a bus from N Main St & E Cypress St to Key West Airport via Florida Mall, Orlando, and Miami Airport Station in around 10h 56m.

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