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How to get fromKissimmee to Knoxvilleby taxi, plane, bus, shuttle, car, or train

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There are 7 ways to get from Kissimmee to Knoxville by taxi, plane, bus, shuttle, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Orlando Sanford, fly to Mcghee Tyson Airport

    best
    1. Take the taxi from Kissimmee to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    2h 53m
    $272–846

  2. Fly Orlando to Asheville Regional Airport, drive

    cheapest
    1. Fly from Orlando (MCO) to Asheville Regional Airport (AVL)plane plane MCO - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    5h 43m
    $81–350

  3. Bus, taxi, shuttle, drive

    1. Take the bus from N Main St & E Orange St to N Garland Ave & W Amelia Stbus bus 18
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Boonebus bus
    4. Take the taxi from Boone to Black Bear Resorttaxi taxi
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Chilhowee at Holstoncar car
    22h 57m

  4. Train, bus, taxi, shuttle, drive

    1. Take the train from Kissimmee Amtrak Station to Carytrain train
    2. Take the train from Cary to High Pointtrain train
    3. Take the bus from Forsyth Hospital to Boonebus bus
    4. Take the taxi from Boone to Black Bear Resorttaxi taxi
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Knoxvillecar car
    26h 20m

  5. Drive 646.5 mi

    1. Drive from Kissimmee to Knoxvillecar car 646.5 mi
    10h 55m
    $118–171

  6. Fly Orlando to Mcghee Tyson Airport

    1. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    3h 43m
    $159–675

  7. Taxi to Orlando Sanford, fly to Asheville Regional Airport, drive

    1. Take the taxi from Kissimmee to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    4h 46m
    $184–491

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration1h 38mAverage Duration
Ticket$114Cheapest Price
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Questions & Answers

Map of how to get from Kissimmee to Knoxville.ExpandLaunch map view
  • Distance: 562.7 mi
  • Duration: 2h 53m

What companies run services between Kissimmee, FL, USA and Knoxville, TN, USA?

Allegiant Air, Southwest Airlines, and two other airlines fly from Orlando (MCO) to Mcghee Tyson Airport (TYS) every 4 hours.

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