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How to get fromKissimmee to St. Louisby plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or taxi

Find Transport to St. Louis

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There are 7 ways to get from Kissimmee to St. Louis by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Lambert–St. Louis International Airport

    best
    1. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    5h 3m
    $187–248

  2. Train to Tampa, fly to Lambert–St. Louis International Airport

    cheapest
    1. Take the train from Kissimmee Amtrak Station to Tampatrain train
    2. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    7h 9m
    $150–623

  3. Bus via N Garland Ave & W Amelia St

    1. Take the bus from N Main St & E Orange St to N Garland Ave & W Amelia Stbus bus 18
    2. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    22h 49m
    $157–282

  4. Train (Amtrak)

    1. Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    45h 21m
    $1,103–1,702

  5. Drive  1,000.2 mi

    1. Drive from Kissimmee to St. Louiscar car 1,000.2 mi
    16h 31m
    $177–256

  6. Taxi to Orlando Sanford, fly to Midamerica St. Louis Airport

    1. Take the taxi from Kissimmee to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Midamerica St. Louis Airport (BLV)plane plane SFB - BLV
    4h 25m
    $213–578

  7. Bus

    1. Take the bus from Orlando to Atlanta Bus Stationbus bus FlixBus 2415
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    23h 41m
    $162–272

Kissimmee to St. Louis by bus

Calendar24Weekly Buses
Duration22h 49mAverage Duration
Ticket$157Cheapest Price
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Comparing Your Travel Options

Map of how to get from Kissimmee to St. Louis.ExpandLaunch map view
  • Distance: 924.3 mi
  • Duration: 5h 3m

What companies run services between Kissimmee, FL, USA and St. Louis, MO, USA?

Frontier Airlines, Southwest Airlines, and Delta fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, you can take a bus from N Main St & E Orange St to St Louis Bus Station via N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Atlanta Bus Station in around 22h 49m.

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