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How to get fromKissimmee to St. Louisby plane, bus (Flixbus, Greyhound), train (Amtrak), car, taxi, or train

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There are 7 ways to get from Kissimmee to St. Louis by plane, bus (Flixbus, Greyhound), train (Amtrak), car, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Lambert–St. Louis International Airport

    best
    1. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    4h 58m
    $187–328

  2. Bus

    cheapest
    1. Take the bus from Orlando to Atlanta Bus Stationbus bus FlixBus 2415
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    23h 41m
    $147–262

  3. Bus via LYNX Central

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus FlixBus N2401 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    22h 4m
    $150–265

  4. Train (Amtrak)

    1. Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    45h 21m
    $1,102–1,701

  5. Drive  1,000.2 mi

    1. Drive from Kissimmee to St. Louiscar car 1,000.2 mi
    16h 31m
    $183–264

  6. Taxi to Orlando Sanford, fly to Midamerica St. Louis Airport

    1. Take the taxi from Kissimmee to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Midamerica St. Louis Airport (BLV)plane plane SFB - BLV
    4h 25m
    $213–578

  7. Train to Tampa, fly to Lambert–St. Louis International Airport

    1. Take the train from Kissimmee Amtrak Station to Tampatrain train
    2. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    7h 9m
    $600–2,073

Kissimmee to St. Louis by train and bus

Calendar12Weekly Services
Duration22h 4mAverage Duration
Ticket$150Cheapest Price
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Comparing Your Travel Options

Map of how to get from Kissimmee to St. Louis.ExpandLaunch map view
  • Distance: 924.3 mi
  • Duration: 4h 58m

What companies run services between Kissimmee, FL, USA and St. Louis, MO, USA?

Frontier Airlines, Southwest Airlines, and Delta fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, you can take a train from Kissimmee to St Louis Bus Station via LYNX Central, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Atlanta Bus Station in around 22h 4m.

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