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How to get fromKissimmee to Winston-Salemby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 7 ways to get from Kissimmee to Winston-Salem by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Orlando (MCO) to Piedmont Triad International Airport (GSO)plane plane MCO - GSO
    4h 51m
    $108–518

  2. Fly to Raleigh-Durham International Airport, bus

    cheapest
    1. Fly from Orlando (MCO) to Raleigh-Durham International Airport (RDU)plane plane MCO - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    7h 31m
    $87–325

  3. Bus

    1. Take the bus from N Main St & E Orange St to N Garland Ave & W Amelia Stbus bus 18
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    15h 39m
    $94–182

  4. Train, bus via Fayetteville

    1. Take the train from Kissimmee Amtrak Station to Fayetteville Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Fayetteville to Winston-Salembus bus Winston-Salem to Fayetteville
    16h 20m
    $216–432

  5. Drive 614.1 mi

    1. Drive from Kissimmee to Winston-Salemcar car 614.1 mi
    10h 23m
    $113–162

  6. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Orlando (MCO) to Charlotte Douglas International Airport (CLT)plane plane MCO - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 47m
    $115–391

  7. Train, bus

    1. Take the train from Kissimmee Amtrak Station to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    18h 5m
    $238–481

Kissimmee to Winston-Salem by bus

Calendar7Weekly Buses
Duration15h 39mAverage Duration
Ticket$94Cheapest Price
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Questions & Answers

Map of how to get from Kissimmee to Winston-Salem.ExpandLaunch map view
  • Distance: 588 mi
  • Duration: 4h 51m

What companies run services between Kissimmee, FL, USA and Winston-Salem, NC, USA?

Breeze Airways, American Airlines, and two other airlines fly from Orlando (MCO) to Piedmont Triad International Airport (GSO) every 2 hours. Alternatively, you can take a bus from N Main St & E Orange St to Winston Salem(Trans Center) via N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Charlotte Bus Station in around 15h 39m.

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