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How to get fromKnoxville to St. Louisby taxi, plane, bus, train, car, or bus (Greyhound)

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There are 4 ways to get from Knoxville to St. Louis by taxi, plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Knoxville to Des-Moines-Airport-DSMtaxi taxi
    2. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    5h 21m
    $225–900

  2. Drive 294.5 mi

    cheapest
    1. Drive from Knoxville to St. Louiscar car 294.5 mi
    6h 6m
    $54–78

  3. Bus, train

    1. Take the bus from Oskaloosa to Bloomington-Normalbus bus Greyhound US0157S
    2. Take the train from Bloomington-Normal to St. Louistrain train Lincoln Service / ...
    9h 20m
    $137–247

  4. Bus (Greyhound)

    1. Take the bus from Monroe to Des Moinesbus bus Greyhound US0157S
    2. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    10h 20m
    $98–169

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar134Weekly Planes
Duration5h 27mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to St. Louis.ExpandLaunch map view
  • Distance: 309.1 mi
  • Duration: 5h 21m

What companies run services between Knoxville, IA, USA and St. Louis, MO, USA?

You can take a vehicle from Knoxville to St Louis Bus Station via Monroe and Des Moines in around 10h 20m.

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