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How to get fromKnoxville to Alpenaby plane, bus (Greyhound), car, bus, train, shuttle, or taxi

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There are 6 ways to get from Knoxville to Alpena by plane, bus (Greyhound), car, bus, train, shuttle, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Alpena County Regional Airport (APN)plane plane TYS - APN
    5h 58m
    $165–552

  2. Drive to Chattanooga Metropolitan Airport, fly

    cheapest
    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Alpena County Regional Airport (APN)plane plane CHA - APN
    10h 13m
    $122–462

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Greyhound to Alpenabus bus
    24h 49m
    $258–406

  4. Drive  722.4 mi

    1. Drive from Knoxville to Alpenacar car 722.4 mi
    12h 42m
    $132–191

  5. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Flint Amtrak Stationtrain train
    4. Take the bus from Flint Amtrak to Alpenabus bus
    26h 51m
    $303–521

  6. Drive, shuttle, taxi, bus

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Boonetaxi taxi
    4. Take the bus from Boone to Charlottebus bus
    5. Take the bus from Charlotte Bus Station to Detroit Bus Stationbus bus
    6. Take the bus from Detroit Greyhound to Alpenabus bus
    33h 30m
    $427–597

Mcghee Tyson Airport (TYS) to Alpena County Regional Airport (APN) flights

Calendar10Weekly Planes
Duration6h 47mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Alpena.ExpandLaunch map view
  • Distance: 661.8 mi
  • Duration: 5h 58m

What companies run services between Knoxville, TN, USA and Alpena, MI, USA?

Delta flies from Mcghee Tyson Airport (TYS) to Alpena County Regional Airport (APN) once daily. Alternatively, you can take a vehicle from Knoxville to Alpena via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Detroit Greyhound, and Alpena in around 24h 49m.

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