There are 4 ways to get from Knoxville to Alpena by plane, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Mcghee Tyson Airport
best- Fly from Mcghee Tyson Airport (TYS) to Alpena County Regional Airport (APN)plane TYS - APN
6h 4m$155–482Drive to Chattanooga Metropolitan Airport, fly
cheapest- Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car
- Fly from Chattanooga Metropolitan Airport (CHA) to Alpena County Regional Airport (APN)plane CHA - APN
10h 57m$116–461Bus
- Take the bus from Knoxville to Nashvillebus Nyc
- Take the bus from Nashville Bus Station to Detroit Bus Stationbus
- Take the bus from Detroit to Bay Citybus
- Take the bus from Bay City to Alpenabus
25h 44m$285–416Drive 722.4 mi
- Drive from Knoxville to Alpenacar 722.4 mi
12h 42m$128–185
Mcghee Tyson Airport (TYS) to Alpena County Regional Airport (APN) flights
Comparing Your Travel Options
The cheapest way to get from Knoxville to Alpena is to drive which costs $120 - $190 and takes 12h 42m.
The fastest way to get from Knoxville to Alpena is to fly which takes 6h 4m and costs $150 - $490.
No, there is no direct bus from Knoxville to Alpena. However, there are services departing from Knoxville and arriving at Alpena via Charlotte Pike & Lellyett St Eb, Central 4Th Ave - Bay 13, Nashville Bus Station, Detroit and Bay City. The journey, including transfers, takes approximately 25h 44m.
The distance between Knoxville and Alpena is 666 miles. The road distance is 726.6 miles.
The best way to get from Knoxville to Alpena without a car is to bus which takes 25h 44m and costs $280 - $420.
It takes approximately 6h 4m to get from Knoxville to Alpena, including transfers.
Knoxville to Alpena bus services, operated by Wanda Coach, depart from Knoxville station.
The best way to get from Knoxville to Alpena is to fly which takes 6h 4m and costs $150 - $490. Alternatively, you can bus, which costs $280 - $420 and takes 25h 44m.
Knoxville to Alpena bus services, operated by Wanda Coach, arrive at Nashville station.
Yes, the driving distance between Knoxville to Alpena is 727 miles. It takes approximately 12h 42m to drive from Knoxville to Alpena.
What companies run services between Knoxville, TN, USA and Alpena, MI, USA?
Delta flies from Mcghee Tyson Airport (TYS) to Alpena County Regional Airport (APN) once daily. Alternatively, you can take a vehicle from Knoxville to Alpena via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Detroit, Bay City, and Alpena in around 25h 44m.
- Website
- delta.com
Flights from Mcghee Tyson Airport to Alpena County Regional Airport via Detroit
- Ave. Duration
- 5h 26m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $70–380
Flights from Mcghee Tyson Airport to Alpena County Regional Airport via Atlanta, Detroit
- Ave. Duration
- 8h 36m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $85–440
Flights from Chattanooga Metropolitan Airport to Alpena County Regional Airport via Detroit
- Ave. Duration
- 14h 56m
- When
- Every day
- Estimated price
- $70–400
Flights from Chattanooga Metropolitan Airport to Alpena County Regional Airport via Atlanta, Detroit
- Ave. Duration
- 11h 31m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–430
Flights from Chattanooga Metropolitan Airport to Alpena County Regional Airport via New York La Guardia, Detroit
- Ave. Duration
- 11h 11m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Chattanooga Metropolitan Airport to Alpena County Regional Airport via Charlotte, Detroit
- Ave. Duration
- 9h 26m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–440
Flights from Chattanooga Metropolitan Airport to Alpena County Regional Airport via Reagan Washington, Detroit
- Ave. Duration
- 10h 11m
- When
- Monday and Thursday
- Estimated price
- $95–470
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Knoxville to Nashville
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $40–60
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Nashville Bus Station to Detroit Bus Station
- Ave. Duration
- 12h 5m
- Frequency
- Twice daily
- Estimated price
- $100–150
- Website
- Greyhound
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Detroit to Bay City
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $19–40
- Website
- Indian Trails
Bus from Bay City to Alpena
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $23–45
- Website
- Indian Trails
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Booking & Getting There
There are 12+ hotels available in Alpena.



