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How to get fromKnoxville to Amesby plane, shuttle, bus (Greyhound, Amtrak), car, taxi, or bus (Greyhound)

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There are 7 ways to get from Knoxville to Ames by plane, shuttle, bus (Greyhound, Amtrak), car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines, shuttle

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Des Moines (DSM)plane plane TYS - DSM
    2. Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State Universityshuttle bus
    5h 45m
    $317–1,207

  2. Drive 823.3 mi

    cheapest
    1. Drive from Knoxville to Amescar car 823.3 mi
    14h 32m
    $151–217

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    4. Take the bus from Des Moines to Amesbus bus
    23h 24m
    $272–401

  4. Fly to Fort Dodge Municipal Airport, taxi

    1. Fly from Mcghee Tyson Airport (TYS) to Fort Dodge Municipal Airport (FOD)plane plane TYS - FOD
    2. Take the taxi from Fort Dodge Municipal Airport (FOD) to Amestaxi taxi
    6h 36m
    $307–847

  5. Bus via Clarksville Exit 11 Park And Ride

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    5. Take the bus from Des Moines to Amesbus bus
    25h 30m
    $272–436

  6. Bus #2

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Kansas Citybus bus
    3. Take the bus from Kansas City to Des Moinesbus bus
    4. Take the bus from Des Moines to Amesbus bus
    26h 28m
    $304–433

  7. Bus #3

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    4. Take the bus from Des Moines to Amesbus bus
    27h 36m
    $334–583

Mcghee Tyson Airport (TYS) to Des Moines (DSM) flights

Calendar89Weekly Planes
Duration5h 9mAverage Duration
Ticket$189Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Ames.ExpandLaunch map view
  • Distance: 707 mi
  • Duration: 5h 45m

What companies run services between Knoxville, TN, USA and Ames, IA, USA?

You can take a vehicle from Knoxville to Ames via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Indianapolis Union Station, and Des Moines in around 23h 24m.

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