Rome2Rio

How to get fromKnoxville to Amesby plane, shuttle, bus (Greyhound, Flixbus), car, taxi, bus, or train

Find Transport to Ames

See all options

There are 6 ways to get from Knoxville to Ames by plane, shuttle, bus (Greyhound, Flixbus), car, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines, shuttle

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Des Moines (DSM)plane plane TYS - DSM
    2. Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State Universityshuttle bus
    5h 52m
    $287–1,057

  2. Drive  823.3 mi

    cheapest
    1. Drive from Knoxville to Amescar car 823.3 mi
    14h 32m
    $151–217

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    5. Take the bus from Kansas City to Amesbus bus
    22h 35m
    $263–419

  4. Fly to Fort Dodge Municipal Airport, taxi

    1. Fly from Mcghee Tyson Airport (TYS) to Fort Dodge Municipal Airport (FOD)plane plane TYS - FOD
    2. Take the taxi from Fort Dodge Municipal Airport (FOD) to Amestaxi taxi
    6h 33m
    $287–727

  5. Bus, train

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the bus from Kansas City to Amesbus bus
    26h 10m
    $339–575

  6. Bus, taxi

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    4. Take the taxi from Des Moines to Amestaxi taxi
    26h 38m
    $385–551

Mcghee Tyson Airport (TYS) to Des Moines (DSM) flights

Calendar85Weekly Planes
Duration5h 19mAverage Duration
Ticket$153Cheapest Price
See schedules

Questions & Answers

Map of how to get from Knoxville to Ames.ExpandLaunch map view
  • Distance: 707 mi
  • Duration: 5h 52m

What companies run services between Knoxville, TN, USA and Ames, IA, USA?

You can take a vehicle from Knoxville to Ames via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 5Th Ave - Bay 11, Clarksville Exit 11 Park And Ride, Clarksville Park & Ride, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 22h 35m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers