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How to get fromKnoxville to Biloxiby plane, bus (Greyhound, Flixbus), car, bus, or train

Find Transport to Biloxi

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There are 5 ways to get from Knoxville to Biloxi by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT)plane plane TYS - GPT
    4h 2m
    $192–712

  2. Drive 555.5 mi

    cheapest
    1. Drive from Knoxville to Biloxicar car 555.5 mi
    9h 40m
    $102–147

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    4. Take the bus from La Grange Bus Station to Biloxibus bus
    17h 36m
    $253–363

  4. Drive to Asheville Regional Airport, fly

    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Gulfport-Biloxi Regional Airport (GPT)plane plane AVL - GPT
    6h 48m
    $127–477

  5. Bus, train

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    22h 26m
    $235–371

Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT) flights

Calendar67Weekly Planes
Duration5hAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Biloxi.ExpandLaunch map view
  • Distance: 500.6 mi
  • Duration: 4h 2m

What companies run services between Knoxville, TN, USA and Biloxi, MS, USA?

Delta, United Airlines, and American Airlines fly from Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT) every 3 hours. Alternatively, you can take a vehicle from Knoxville to Biloxi via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Atlanta Bus Station, and La Grange Bus Station in around 17h 36m.

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