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How to get fromKnoxville to Blufftonby plane, car, shuttle, bus, train, or taxi

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There are 7 ways to get from Knoxville to Bluffton by plane, car, shuttle, bus, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Hilton Head Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Hilton Head Airport (HHH)plane plane TYS - HHH
    4h 11m
    $152–527

  2. Drive  405.4 mi

    cheapest
    1. Drive from Knoxville to Blufftoncar car 405.4 mi
    7h
    $74–107

  3. Drive, shuttle, bus, train, taxi via Cary

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Forsyth Hospitalbus bus
    5. Take the train from High Point to Carytrain train
    6. Take the train from Cary to Savannah Stationtrain train
    7. Take the taxi from Savannah Station to Blufftontaxi taxi
    20h 26m
    $458–663

  4. Drive, shuttle, bus, train, taxi

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Charlottebus bus
    5. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    6. Take the bus from Sumter Bus Stop to Charleston Bus Stationbus bus
    7. Take the train from Charleston Amtrak Station to Savannah Stationtrain train
    8. Take the taxi from Savannah Station to Blufftontaxi taxi
    20h 49m
    $421–532

  5. Fly to Savannah, taxi

    1. Fly from Mcghee Tyson Airport (TYS) to Savannah (SAV)plane plane TYS - SAV
    2. Take the taxi from Savannah (SAV) to Blufftontaxi taxi
    4h
    $257–897

  6. Drive, shuttle, taxi, bus, train

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Boonetaxi taxi
    4. Take the bus from Boone to Charlottebus bus
    5. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    6. Take the bus from Sumter Bus Stop to Charleston Bus Stationbus bus
    7. Take the train from Charleston Amtrak Station to Savannah Stationtrain train
    8. Take the taxi from Savannah Station to Blufftontaxi taxi
    21h 10m
    $456–597

  7. Bus, train, taxi

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Savannah Stationtrain train
    5. Take the taxi from Savannah Station to Blufftontaxi taxi
    25h 9m
    $369–549

Mcghee Tyson Airport (TYS) to Hilton Head Airport (HHH) flights

Calendar36Weekly Planes
Duration5h 16mAverage Duration
Ticket$67Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Bluffton.ExpandLaunch map view
  • Distance: 335.3 mi
  • Duration: 4h 11m

What companies run services between Knoxville, TN, USA and Bluffton, SC, USA?

Delta, American Airlines, and United Airlines fly from Mcghee Tyson Airport (TYS) to Hilton Head Airport (HHH) 5 times a day.

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