What is the cheapest way to get from Knoxville to Buffalo?

The cheapest way to get from Knoxville to Buffalo is to drive which costs $120 - $180 and takes 11h 35m.

What is the fastest way to get from Knoxville to Buffalo?

The fastest way to get from Knoxville to Buffalo is to fly which takes 5h 27m and costs $190 - $800.

Is there a direct bus between Knoxville and Buffalo?

No, there is no direct bus from Knoxville to Buffalo. However, there are services departing from Knoxville and arriving at Buffalo, NY via El Mezcal Grocery - Jackson, TN, Louisville, KY Bus Station and Cleveland, OH. The journey, including transfers, takes approximately 24h 51m.

How far is it from Knoxville to Buffalo?

The distance between Knoxville and Buffalo is 592 miles. The road distance is 686.6 miles.

How do I travel from Knoxville to Buffalo without a car?

The best way to get from Knoxville to Buffalo without a car is to bus and train which takes 21h 59m and costs $250 - $460.

How long does it take to get from Knoxville to Buffalo?

It takes approximately 5h 27m to get from Knoxville to Buffalo, including transfers.

Where do I catch the Knoxville to Buffalo bus from?

Knoxville to Buffalo bus services, operated by Wanda Coach, depart from Knoxville station.

Bus or fly from Knoxville to Buffalo?

The best way to get from Knoxville to Buffalo is to fly which takes 5h 27m and costs $190 - $800. Alternatively, you can bus, which costs $270 - $430 and takes 24h 51m.

Where does the Knoxville to Buffalo bus arrive?

Knoxville to Buffalo bus services, operated by Wanda Coach, arrive at Jackson station.

Can I drive from Knoxville to Buffalo?

Yes, the driving distance between Knoxville to Buffalo is 687 miles. It takes approximately 11h 35m to drive from Knoxville to Buffalo.

Where can I stay near Buffalo?

There are 266+ hotels available in Buffalo.

Knoxville to Buffalo - 6 ways to travel via train, plane, bus, and car

How to get fromKnoxville to Buffalo

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There are 6 ways to get from Knoxville to Buffalo by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Buffalo Niagara International Airport
best
1. Fly from Mcghee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF)plane TYS - BUF
5h 27m
$192–795
Drive 682.6 mi
cheapest
1. Drive from Knoxville to Buffalocar 682.6 mi
11h 35m
$125–180
Bus, train
1. Take the bus from Knoxville, TN to New York, NYbus Ny
2. Take the train from New York Penn Station to Buffalotrain VIA Rail
21h 59m
$250–453
Fly to Rochester, bus
1. Fly from Mcghee Tyson Airport (TYS) to Rochester (ROC)plane TYS - ROC
2. Take the bus from Rochester Bus Stop to Buffalobus
6h 51m
$245–1,009
Fly to Toronto Island Airport, train
1. Fly from Mcghee Tyson Airport (TYS) to Toronto Island Airport (YTZ)plane TYS - YTZ
2. Take the train from Toronto Union Station to Buffalotrain
9h 45m
$171–697
Bus
1. Take the bus from Knoxville to Jacksonbus Nyc
2. Take the bus from El Mezcal Grocery - Jackson, TN to El Mercadito Grocery - Clarksville, INbus
3. Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus
4. Take the bus from Cleveland, OH to Buffalo, NYbus
24h 51m
$276–429

Mcghee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF) flights

104Weekly Planes

5h 13mAverage Duration

$130Cheapest Price

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Questions & Answers

Map of how to get from Knoxville to Buffalo.

Launch map view

Distance: 588.7 mi
Duration: 5h 27m

What companies run services between Knoxville, TN, USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a vehicle from Knoxville to Buffalo, NY via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, El Mercadito Grocery - Clarksville, IN, Louisville, KY Bus Station, and Cleveland, OH in around 24h 51m.

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