What is the cheapest way to get from Knoxville to Buffalo?

The cheapest way to get from Knoxville to Buffalo is to drive which costs $120 - $180 and takes 11h 35m.

What is the fastest way to get from Knoxville to Buffalo?

The fastest way to get from Knoxville to Buffalo is to fly which takes 5h 17m and costs $180 - $800.

Is there a direct bus between Knoxville and Buffalo?

No, there is no direct bus from Knoxville to Buffalo. However, there are services departing from Knoxville and arriving at Buffalo via El Mezcal Grocery - Jackson, TN, Indianapolis, Toledo and Cleveland. The journey, including transfers, takes approximately 26h 51m.

How far is it from Knoxville to Buffalo?

The distance between Knoxville and Buffalo is 592 miles. The road distance is 686.6 miles.

How do I travel from Knoxville to Buffalo without a car?

The best way to get from Knoxville to Buffalo without a car is to bus and train which takes 21h 59m and costs $250 - $450.

How long does it take to get from Knoxville to Buffalo?

It takes approximately 5h 17m to get from Knoxville to Buffalo, including transfers.

Where do I catch the Knoxville to Buffalo bus from?

Knoxville to Buffalo bus services, operated by Wanda Coach, depart from Knoxville station.

Bus or fly from Knoxville to Buffalo?

The best way to get from Knoxville to Buffalo is to fly which takes 5h 17m and costs $180 - $800. Alternatively, you can bus, which costs $300 - $490 and takes 26h 51m.

Where does the Knoxville to Buffalo bus arrive?

Knoxville to Buffalo bus services, operated by Wanda Coach, arrive at Jackson station.

Can I drive from Knoxville to Buffalo?

Yes, the driving distance between Knoxville to Buffalo is 687 miles. It takes approximately 11h 35m to drive from Knoxville to Buffalo.

Where can I stay near Buffalo?

There are 255+ hotels available in Buffalo.

Knoxville to Buffalo - 6 ways to travel via train, plane, bus, and car

How to get fromKnoxville to Buffalo

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There are 6 ways to get from Knoxville to Buffalo by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Buffalo Niagara International Airport
best
1. Fly from Mcghee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF)plane TYS - BUF
5h 17m
$182–795
Drive 682.6 mi
cheapest
1. Drive from Knoxville to Buffalocar 682.6 mi
11h 35m
$125–180
Bus, train
1. Take the bus from Knoxville, TN to New York, NYbus Ny
2. Take the train from New York Penn Station to Buffalotrain VIA Rail
21h 59m
$250–443
Fly to Rochester, bus
1. Fly from Mcghee Tyson Airport (TYS) to Rochester (ROC)plane TYS - ROC
2. Take the bus from Rochester Bus Stop to Buffalobus
6h 50m
$256–1,108
Bus
1. Take the bus from Knoxville to Jacksonbus Nyc
2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus
3. Take the bus from Indianapolis to Toledobus
4. Take the bus from Toledo to Clevelandbus
5. Take the bus from Cleveland to Buffalobus
26h 51m
$300–486
Bus, train via Speedway
1. Take the bus from Knoxville to Jacksonbus Nyc
2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus
3. Take the bus from Indianapolis to Toledobus
4. Take the train from Toledo to Buffalo Depew Stationtrain
27h 39m
$353–731

Mcghee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF) flights

102Weekly Planes

4h 57mAverage Duration

$128Cheapest Price

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Map of how to get from Knoxville to Buffalo.

Launch map view

Distance: 588.7 mi
Duration: 5h 17m

What companies run services between Knoxville, TN, USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a vehicle from Knoxville to Buffalo via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Indianapolis, Indianapolis, Toledo, and Cleveland in around 26h 51m.

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