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How to get fromKnoxville to Cambridgeby plane, bus, train, car, shuttle, or taxi

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There are 6 ways to get from Knoxville to Cambridge by plane, bus, train, car, shuttle, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Boston Logan Airport (BOS)plane plane TYS - BOS
    3h 11m
    $176–676

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Boston Logan Airport (BOS)plane plane AVL - BOS
    4h 56m
    $106–431

  3. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train Acela
    16h 54m
    $210–323

  4. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Bristol Exit 5 Park & Ride Lot to Christiansburgbus bus
    5. Take the bus from Exit 118 - Park and Ride to Roanoke Campbell Courtbus bus Swb
    6. Take the train from Roanoke to Bostontrain train
    27h 52m
    $483–762

  5. Drive 908.3 mi

    1. Drive from Knoxville to Cambridgecar car 908.3 mi
    15h 55m
    $166–240

  6. Drive, shuttle, taxi, bus, train via Washington

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Bristol Exit 5 Park & Ride Lot to Washington Union Stationbus bus
    5. Take the train from Washington Union Station to Bostontrain train
    21h 5m
    $435–641

Mcghee Tyson Airport (TYS) to Boston Logan Airport (BOS) flights

Calendar71Weekly Planes
Duration4h 41mAverage Duration
Ticket$117Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Cambridge.ExpandLaunch map view
  • Distance: 851.8 mi
  • Duration: 3h 11m

What companies run services between Knoxville, TN, USA and Cambridge, MA, USA?

Allegiant Air, Southwest Airlines, and three other airlines fly from Mcghee Tyson Airport (TYS) to Boston Logan Airport (BOS) every 3 hours.

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