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How to get fromKnoxville to Cape Girardeauby bus, car, plane, or taxi

Find Transport to Cape Girardeau

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There are 5 ways to get from Knoxville to Cape Girardeau by bus, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive

    best
    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Cape Girardeaucar car
    8h 59m
    $166–228

  2. Drive 376.4 mi

    cheapest
    1. Drive from Knoxville to Cape Girardeaucar car 376.4 mi
    6h 41m
    $69–100

  3. Fly to Barkley Regional Airport, taxi

    1. Fly from Mcghee Tyson Airport (TYS) to Barkley Regional Airport (PAH)plane plane TYS - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    7h 35m
    $317–837

  4. Fly to Lambert–St. Louis International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL)plane plane TYS - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 19m
    $194–814

  5. Fly to Cape Girardeau Municipal Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Cape Girardeau Municipal Airport (CGI)plane plane TYS - CGI
    7h 25m
    $200–695

Mcghee Tyson Airport (TYS) to Barkley Regional Airport (PAH) flights

Calendar21Weekly Planes
Duration6h 46mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Cape Girardeau.ExpandLaunch map view
  • Distance: 395.8 mi
  • Duration: 8h 59m

What companies run services between Knoxville, TN, USA and Cape Girardeau, MO, USA?

United Airlines, Corporate Flight Management Inc, and three other airlines fly from Mcghee Tyson Airport (TYS) to Cape Girardeau Municipal Airport (CGI) twice daily.

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