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How to get fromKnoxville to Casperby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 6 ways to get from Knoxville to Casper by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Casper (CPR)plane plane TYS - CPR
    6h 6m
    $179–632

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Casper (CPR)plane plane AVL - CPR
    8h 18m
    $154–597

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Denver Union Stationbus bus
    4. Take the bus from Denver to Casperbus bus
    36h 49m
    $423–594

  4. Bus, train

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the train from Indianapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Denvertrain train
    5. Take the bus from Denver to Casperbus bus
    47h 57m
    $990–1,496

  5. Drive  1,490.1 mi

    1. Drive from Knoxville to Caspercar car 1,490.1 mi
    24h 47m
    $272–393

  6. Bus via New South Memphis

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Cheyennebus bus
    5. Take the bus from Cheyenne to Casperbus bus
    38h 58m
    $451–646

Mcghee Tyson Airport (TYS) to Casper (CPR) flights

Calendar21Weekly Planes
Duration6hAverage Duration
Ticket$115Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Casper.ExpandLaunch map view
  • Distance: 1,315.4 mi
  • Duration: 6h 6m

What companies run services between Knoxville, TN, USA and Casper, WY, USA?

United Airlines, Southwest Airlines, and Allegiant Air fly from Mcghee Tyson Airport (TYS) to Casper (CPR) 3 times a day. Alternatively, you can take a vehicle from Knoxville to Casper via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, St Louis Bus Station, Denver Union Station, and Denver in around 36h 49m.

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