There are 4 ways to get from Knoxville to Charleston Amtrak Station by plane, car, shuttle, bus, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS)plane TYS - CHS
5h 19m$136–551Drive 364.3 mi
cheapest- Drive from Knoxville to Charleston Amtrak Stationcar 364.3 mi
6h 13m$67–96Drive, shuttle, bus
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte Bus Station to Charleston Bus Stationbus
16h 10m$369–442Drive, shuttle, taxi, bus
- Drive from Chilhowee at Holston to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take the taxi from Black Bear Resort to ASU Peacock Hall Boonetaxi
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte Bus Station to Charleston Bus Stationbus
16h 32m$404–507
Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS) flights
Questions & Answers
The cheapest way to get from Knoxville to Charleston Amtrak Station is to drive which costs $65 - $100 and takes 6h 13m.
The fastest way to get from Knoxville to Charleston Amtrak Station is to fly which takes 5h 19m and costs $130 - $550.
The distance between Knoxville and Charleston Amtrak Station is 322 miles. The road distance is 366.4 miles.
It takes approximately 5h 19m to get from Knoxville to Charleston Amtrak Station, including transfers.
Yes, the driving distance between Knoxville to Charleston Amtrak Station is 366 miles. It takes approximately 6h 13m to drive from Knoxville to Charleston Amtrak Station.
There are 1483+ hotels available in Charleston Amtrak Station.
What companies run services between Knoxville, TN, USA and Charleston Amtrak Station, SC, USA?
Delta, American Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS) hourly.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $75–480
Flights from Mcghee Tyson Airport to Charleston International Airport via Reagan Washington
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $130–650
- Website
- delta.com
Flights from Mcghee Tyson Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $80–500
- Website
- united.com
Flights from Mcghee Tyson Airport to Charleston International Airport via Washington Dulles
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $120–650
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Charleston International Airport via Baltimore
- Ave. Duration
- 5h 52m
- When
- Tuesday to Friday
- Estimated price
- $130–700
Flights from Mcghee Tyson Airport to Charleston International Airport via Nashville
- Ave. Duration
- 5h 50m
- When
- Monday, Thursday, and Friday
- Estimated price
- $100–600
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- Black Bear Resort Shuttle
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
- Phone
- +1 828-327-2340
- [email protected]
- Website
- Hickory Hop
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- Hickory Hop
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- Hickory Hop
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charlotte Bus Station to Charleston Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Charlotte Bus Station to Charleston Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Greyhound
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