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How to get fromKnoxville to Charlestonby plane, car, shuttle, taxi, bus, or train

Find Transport to Charleston

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There are 4 ways to get from Knoxville to Charleston by plane, car, shuttle, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS)plane plane TYS - CHS
    5h 10m
    $134–549

  2. Drive 372.6 mi

    cheapest
    1. Drive from Knoxville to Charlestoncar car 372.6 mi
    6h 22m
    $68–99

  3. Drive, shuttle, taxi, bus, train

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Bristol Exit 5 Park & Ride Lot to Washington Union Stationbus bus
    5. Take the train from Washington Union Station to Charleston Amtrak Stationtrain train
    25h 43m
    $459–675

  4. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    28h 8m
    $400–683

Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS) flights

Calendar106Weekly Planes
Duration4h 29mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Charleston.ExpandLaunch map view
  • Distance: 329.3 mi
  • Duration: 5h 10m

What companies run services between Knoxville, TN, USA and Charleston, SC, USA?

Delta, American Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS) hourly.

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