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How to get fromKnoxville to Cheyenneby plane, bus (Greyhound, Flixbus), bus, train, car, taxi, or bus (Greyhound)

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There are 8 ways to get from Knoxville to Cheyenne by plane, bus (Greyhound, Flixbus), bus, train, car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Cheyenne Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Cheyenne Airport (CYS)plane plane TYS - CYS
    6h 26m
    $197–717

  2. Drive to Asheville Regional Airport, fly to Cheyenne Airport

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Cheyenne Airport (CYS)plane plane AVL - CYS
    7h 20m
    $142–582

  3. Bus

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Cheyennebus bus
    35h 38m
    $379–610

  4. Bus, train

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the train from Indianapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Denvertrain train
    5. Take the bus from Denver International Airport Pickups to Warren AFBbus bus
    45h 9m
    $655–1,186

  5. Drive 1,361.5 mi

    1. Drive from Knoxville to Cheyennecar car 1,361.5 mi
    22h 3m
    $249–359

  6. Fly Mcghee Tyson Airport to Laramie Regional Airport, taxi

    1. Fly from Mcghee Tyson Airport (TYS) to Laramie Regional Airport (LAR)plane plane TYS - LAR
    2. Take the taxi from Laramie-Airport-LAR to Cheyennetaxi taxi
    6h 33m
    $297–837

  7. Fly Mcghee Tyson Airport to Denver, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Denver (DEN)plane plane TYS - DEN
    2. Take the bus from Denver International Airport Pickups to Warren AFBbus bus
    6h 42m
    $247–807

  8. Bus via Indianapolis

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Denver Union Stationbus bus
    5. Take the bus from Denver Union Station to Cheyennebus bus
    42h 11m
    $445–681

Mcghee Tyson Airport (TYS) to Cheyenne Airport (CYS) flights

Calendar20Weekly Planes
Duration7h 23mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Cheyenne.ExpandLaunch map view
  • Distance: 1,194.9 mi
  • Duration: 6h 26m

What companies run services between Knoxville, TN, USA and Cheyenne, WY, USA?

United Airlines, Southwest Airlines, and Allegiant Air fly from Mcghee Tyson Airport (TYS) to Cheyenne Airport (CYS) 3 times a day. Alternatively, you can take a vehicle from Knoxville to Cheyenne Regional Medical Center via Knoxville, Memphis - Summer Ave, Memphis Bus Station, St Louis Bus Station, Denver Union Station, and Greyhound in around 35h 38m.

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