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How to get fromKnoxville to Cheyenneby plane, bus (Greyhound, Flixbus), bus, train, car, taxi, or bus (Greyhound)

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There are 7 ways to get from Knoxville to Cheyenne by plane, bus (Greyhound, Flixbus), bus, train, car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cheyenne Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Cheyenne Airport (CYS)plane plane TYS - CYS
    6h 21m
    $187–717

  2. Bus

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Cheyennebus bus
    35h 38m
    $369–550

  3. Bus, train

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the train from Indianapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Denvertrain train
    5. Take the bus from Denver International Airport Pickups to Warren AFBbus bus
    45h 9m
    $950–1,476

  4. Drive  1,361.5 mi

    1. Drive from Knoxville to Cheyennecar car 1,361.5 mi
    22h 3m
    $249–359

  5. Fly to Laramie Regional Airport, taxi

    1. Fly from Mcghee Tyson Airport (TYS) to Laramie Regional Airport (LAR)plane plane TYS - LAR
    2. Take the taxi from Laramie-Airport-LAR to Cheyennetaxi taxi
    7h 39m
    $287–837

  6. Fly to Denver, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Denver (DEN)plane plane TYS - DEN
    2. Take the bus from Denver International Airport Pickups to Warren AFBbus bus
    6h 43m
    $237–807

  7. Bus via Indianapolis

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Denver Union Stationbus bus
    5. Take the bus from Denver Union Station to Cheyennebus bus
    42h 11m
    $440–626

Mcghee Tyson Airport (TYS) to Cheyenne Airport (CYS) flights

Calendar22Weekly Planes
Duration7h 3mAverage Duration
Ticket$132Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Cheyenne.ExpandLaunch map view
  • Distance: 1,194.9 mi
  • Duration: 6h 21m

What companies run services between Knoxville, TN, USA and Cheyenne, WY, USA?

United Airlines, Southwest Airlines, and Allegiant Air fly from Mcghee Tyson Airport (TYS) to Cheyenne Airport (CYS) 3 times a day. Alternatively, you can take a vehicle from Knoxville to Cheyenne Regional Medical Center via Knoxville, Memphis - Summer Ave, Memphis Bus Station, St Louis Bus Station, Denver Union Station, and Greyhound in around 35h 38m.

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