There are 6 ways to get from Knoxville to Chicago Union Station by plane, bus (Greyhound, Flixbus), car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Mcghee Tyson Airport to Chicago O'Hare International Airport
best- Fly from Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD)plane TYS - ORD
3h 11m$129–482Drive to Asheville Regional Airport, fly to Chicago O'Hare International Airport
cheapest- Drive from Knoxville to Asheville-Airport-AVLcar
- Fly from Asheville Regional Airport (AVL) to Chicago O'Hare International Airport (ORD)plane AVL - ORD
5h 14m$74–327Bus
- Take the bus from Knoxville to Nashvillebus Nyc
- Take the bus from Nashville Bus Station to Chicago Bus Stationbus Greyhound US0100
15h 4m$203–309Drive 527.6 mi
- Drive from Knoxville to Chicago Union Stationcar 527.6 mi
9h 13m$97–140Fly Mcghee Tyson Airport to Chicago Midway International Airport, subway
- Fly from Mcghee Tyson Airport (TYS) to Chicago Midway International Airport (MDW)plane TYS - MDW
- Take the subway from Midway to Quincysubway
2h 42m$139–542Drive to Chattanooga Metropolitan Airport, fly to Chicago O'Hare International Airport
- Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car
- Fly from Chattanooga Metropolitan Airport (CHA) to Chicago O'Hare International Airport (ORD)plane CHA - ORD
4h 48m$106–522
Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD) flights
Questions & Answers
The cheapest way to get from Knoxville to Chicago Union Station is to drive which costs $95 - $140 and takes 9h 13m.
The fastest way to get from Knoxville to Chicago Union Station is to fly and subway which takes 2h 42m and costs $130 - $550.
No, there is no direct bus from Knoxville to Chicago Union Station station. However, there are services departing from Knoxville and arriving at Chicago Bus Station via Charlotte Pike & Lellyett St Eb, Central 4Th Ave - Bay 13 and Nashville Bus Station. The journey, including transfers, takes approximately 15h 4m.
The distance between Knoxville and Chicago Union Station is 509 miles. The road distance is 530.6 miles.
The best way to get from Knoxville to Chicago Union Station without a car is to bus which takes 15h 4m and costs $200 - $310.
It takes approximately 3h 11m to get from Knoxville to Chicago Union Station, including transfers.
Knoxville to Chicago Union Station bus services, operated by Wanda Coach, depart from Knoxville station.
The best way to get from Knoxville to Chicago Union Station is to fly which takes 3h 11m and costs $120 - $490. Alternatively, you can bus, which costs $200 - $310 and takes 15h 4m.
Knoxville to Chicago Union Station bus services, operated by Wanda Coach, arrive at Nashville station.
Chicago Union Station is 1h behind Knoxville. It is currently 1:38 AM in Knoxville and 12:38 AM in Chicago Union Station.
What companies run services between Knoxville, TN, USA and Chicago Union Station, IL, USA?
American Airlines, United Airlines, and Delta fly from Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, you can take a vehicle from Knoxville to Chicago Union Station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, and Chicago Bus Station in around 15h 4m.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $70–410
Flights from Mcghee Tyson Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $95–480
Flights from Chattanooga Metropolitan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- $85–490
Flights from Chattanooga Metropolitan Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $120–600
Flights from Asheville Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $50–290
Flights from Asheville Regional Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $60–320
- Website
- delta.com
Flights from Mcghee Tyson Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $90–470
Flights from Mcghee Tyson Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $85–450
Flights from Chattanooga Metropolitan Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $100–550
Flights from Chattanooga Metropolitan Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 27m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Asheville Regional Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $65–330
- Website
- united.com
Flights from Mcghee Tyson Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $70–410
Flights from Chattanooga Metropolitan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 8m
- When
- Every day
- Estimated price
- $85–490
Flights from Asheville Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $50–290
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Chicago Midway International Airport via Nashville
- Ave. Duration
- 3h 30m
- When
- Saturday to Wednesday
- Estimated price
- $90–500
- Website
- allegiantair.com
Flights from Mcghee Tyson Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 34m
- When
- Thursday
- Estimated price
- $80–470
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Midway to Quincy
- Ave. Duration
- 27 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from Knoxville to Nashville
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $40–60
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 10h
- Frequency
- 4 times a day
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 15m
- Frequency
- Twice daily
- Estimated price
- $75–130
- Schedules at
- flixbus.com
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More Questions & Answers
Yes, the driving distance between Knoxville to Chicago Union Station is 531 miles. It takes approximately 9h 13m to drive from Knoxville to Chicago Union Station.
There are 1302+ hotels available in Chicago Union Station.