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How to get fromKnoxville to Clarksdaleby plane, bus, car, or bus (Greyhound, Flixbus)

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There are 4 ways to get from Knoxville to Clarksdale by plane, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, bus

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Memphis (MEM)plane plane TYS - MEM
    2. Take the bus from Memphis to Clarksdalebus bus
    5h 19m

  2. Drive 460.7 mi

    cheapest
    1. Drive from Knoxville to Clarksdalecar car 460.7 mi
    7h 49m
    $85–122

  3. Bus

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis to Clarksdalebus bus Dea 3 / ...
    9h 33m

  4. Bus via Nashville

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis to Clarksdalebus bus
    10h 39m

Mcghee Tyson Airport (TYS) to Memphis (MEM) flights

Calendar31Weekly Planes
Duration3h 3mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Clarksdale.ExpandLaunch map view
  • Distance: 427.9 mi
  • Duration: 5h 19m

What companies run services between Knoxville, TN, USA and Clarksdale, MS, USA?

You can take a vehicle from Knoxville to Clarksdale via Knoxville, Memphis - Summer Ave, and Memphis in around 9h 33m.

Airlines
Bus operators

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