Rome2Rio

How to get fromKnoxville to Clevelandby plane, bus (Greyhound), car, bus, shuttle, taxi, or train

Find Transport to Cleveland

See all options

There are 5 ways to get from Knoxville to Cleveland by plane, bus (Greyhound), car, bus, shuttle, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Cleveland-Hopkins International Airport (CLE)plane plane TYS - CLE
    4h 33m
    $155–670

  2. Drive  498.8 mi

    cheapest
    1. Drive from Knoxville to Clevelandcar car 498.8 mi
    8h 24m
    $91–132

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus Greyhound US0105
    18h 1m
    $221–312

  4. Bus via Louisville

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to El Mercadito Grocery - Clarksville, INbus bus
    3. Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus bus
    20h 41m
    $258–369

  5. Drive, shuttle, taxi, bus, train

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Bristol Exit 5 Park & Ride Lot to Washington Union Stationbus bus
    5. Take the train from Washington Union Station to Cleveland Amtraktrain train
    25h 26m
    $405–591

Mcghee Tyson Airport (TYS) to Cleveland-Hopkins International Airport (CLE) flights

Calendar131Weekly Planes
Duration4h 24mAverage Duration
Ticket$98Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Knoxville to Cleveland.ExpandLaunch map view
  • Distance: 428.1 mi
  • Duration: 4h 33m

What companies run services between Knoxville, TN, USA and Cleveland, OH, USA?

Delta, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a vehicle from Knoxville to Tower City Station Track 13 via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Cleveland Bus Station, and Brookpark Station in around 18h 1m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There