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How to get fromKnoxville to Clevelandby plane, bus (Greyhound), car, bus, shuttle, taxi, or train

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There are 5 ways to get from Knoxville to Cleveland by plane, bus (Greyhound), car, bus, shuttle, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Cleveland-Hopkins International Airport (CLE)plane plane TYS - CLE
    4h 9m
    $190–770

  2. Drive 498.8 mi

    cheapest
    1. Drive from Knoxville to Clevelandcar car 498.8 mi
    8h 24m
    $91–132

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus Greyhound US0105
    18h 1m
    $226–342

  4. Bus via Louisville

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to El Mercadito Grocery - Clarksville, INbus bus
    3. Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus bus
    20h 43m
    $257–462

  5. Drive, shuttle, taxi, bus, train

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Bristol Exit 5 Park & Ride Lot to Washington Union Stationbus bus
    5. Take the train from Washington Union Station to Cleveland Amtraktrain train
    25h 26m
    $435–631

Mcghee Tyson Airport (TYS) to Cleveland-Hopkins International Airport (CLE) flights

Calendar116Weekly Planes
Duration4h 26mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Cleveland.ExpandLaunch map view
  • Distance: 428.1 mi
  • Duration: 4h 9m

What companies run services between Knoxville, TN, USA and Cleveland, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from Mcghee Tyson Airport (TYS) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a vehicle from Knoxville to Tower City Station Track 13 via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Cleveland Bus Station, and Brookpark Station in around 18h 1m.

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