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How to get fromKnoxville to Columbusby plane, bus, or car

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There are 5 ways to get from Knoxville to Columbus by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Golden Triangle Regional Airport (GTR)plane plane TYS - GTR
    4h 30m
    $167–582

  2. Drive 370.3 mi

    cheapest
    1. Drive from Knoxville to Columbuscar car 370.3 mi
    6h 20m
    $68–98

  3. Bus, drive

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    3. Drive from Tupelo to Columbuscar car
    11h 6m
    $200–276

  4. Bus, drive via Nashville

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    4. Drive from Tupelo to Columbuscar car
    12h 12m
    $189–275

  5. Bus, drive via Walmart

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    3. Drive from Tupelo to Columbuscar car
    16h 36m
    $135–191

Mcghee Tyson Airport (TYS) to Golden Triangle Regional Airport (GTR) flights

Calendar14Weekly Planes
Duration5h 48mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Columbus.ExpandLaunch map view
  • Distance: 332.2 mi
  • Duration: 4h 30m

What companies run services between Knoxville, TN, USA and Columbus, MS, USA?

Delta and American Airlines fly from Mcghee Tyson Airport (TYS) to Golden Triangle Regional Airport (GTR) twice daily.

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