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How to get fromKnoxville to Columbusby plane, bus (Greyhound), or car

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There are 3 ways to get from Knoxville to Columbus by plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to John Glenn Columbus International Airport (CMH)plane plane TYS - CMH
    5h
    $179–820

  2. Drive 357.1 mi

    cheapest
    1. Drive from Knoxville to Columbuscar car 357.1 mi
    6h 2m
    $66–95

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Columbusbus bus Greyhound US0105
    14h 9m
    $193–289

Mcghee Tyson Airport (TYS) to John Glenn Columbus International Airport (CMH) flights

Calendar117Weekly Planes
Duration4h 23mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Columbus.ExpandLaunch map view
  • Distance: 321.6 mi
  • Duration: 5h

What companies run services between Knoxville, TN, USA and Columbus, OH, USA?

Delta, American Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to John Glenn Columbus International Airport (CMH) hourly. Alternatively, you can take a vehicle from Knoxville to Columbus via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, and Nashville Bus Station in around 14h 9m.

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