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How to get fromKnoxville to Detroitby plane, bus (Greyhound), or car

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There are 4 ways to get from Knoxville to Detroit by plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Detroit (DTW)plane plane TYS - DTW
    3h 24m
    $159–669

  2. Drive 508.8 mi

    cheapest
    1. Drive from Knoxville to Detroitcar car 508.8 mi
    8h 38m
    $93–135

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Detroit Bus Stationbus bus Greyhound US0135 / ...
    16h 59m
    $218–329

  4. Drive to Chattanooga Metropolitan Airport, fly

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Detroit (DTW)plane plane CHA - DTW
    5h 4m
    $141–729

Mcghee Tyson Airport (TYS) to Detroit (DTW) flights

Calendar72Weekly Planes
Duration3h 41mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Detroit.ExpandLaunch map view
  • Distance: 478.4 mi
  • Duration: 3h 24m

What companies run services between Knoxville, TN, USA and Detroit, MI, USA?

Delta, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Detroit (DTW) every 3 hours. Alternatively, you can take a vehicle from Knoxville to Detroit Bus Station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, and Nashville Bus Station in around 16h 59m.

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