There are 4 ways to get from Knoxville to Duke University by plane, car, shuttle, taxi, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU)plane TYS - RDU
5h 42m$129–504Drive 320.3 mi
cheapest- Drive from Knoxville to Duke Universitycar 320.3 mi
6h 6m$59–85Drive, shuttle, taxi, bus, train
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take the taxi from Black Bear Resort to Boonetaxi
- Take the bus from Boone to Forsyth Hospitalbus
- Take the train from High Point to Durham Amtrak Stationtrain
11h 23m$306–375Drive, shuttle, bus, train
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from Boone to Forsyth Hospitalbus
- Take the train from High Point to Durham Amtrak Stationtrain
11h 57m$270–309
Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU) flights
Questions & Answers
The cheapest way to get from Knoxville to Duke University is to drive which costs $55 - $85 and takes 6h 6m.
The fastest way to get from Knoxville to Duke University is to fly which takes 5h 42m and costs $120 - $550.
The distance between Knoxville and Duke University is 324 miles. The road distance is 322.2 miles.
It takes approximately 5h 42m to get from Knoxville to Duke University, including transfers.
Yes, the driving distance between Knoxville to Duke University is 322 miles. It takes approximately 6h 6m to drive from Knoxville to Duke University.
There are 403+ hotels available in Duke University.
What companies run services between Knoxville, TN, USA and Duke University, NC, USA?
American Airlines, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU) hourly.
- Website
- delta.com
Flights from Mcghee Tyson Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $80–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from High Point to Durham Amtrak Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $18–45
- Website
- Amtrak
Train from High Point to Durham Amtrak Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $18–45
- Website
- Amtrak
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- Black Bear Resort Shuttle
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