There are 4 ways to get from Knoxville to Duke University by plane, car, shuttle, bus, taxi, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU)plane TYS - RDU
5h 42m$139–554Drive 316.3 mi
cheapest- Drive from Knoxville to Duke Universitycar 316.3 mi
6h 15m$58–84Drive, shuttle, bus
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte, NC - 3302 Queen City Dr to Durham, NC - 3446 Hillsborough Rdbus
12h 27m$356–414Drive, shuttle, taxi, bus, train
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take the taxi from Black Bear Resort to Blowing Rock - Tanger Outletstaxi
- Take the bus from Blowing Rock - Tanger Outlets to Hickory Airportbus
- Take the taxi from Hickory Airport to Callabridge Ct @ Walmarttaxi
- Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
12h 51m$492–629
Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU) flights
Questions & Answers
The cheapest way to get from Knoxville to Duke University is to drive which costs $55 - $85 and takes 6h 15m.
The fastest way to get from Knoxville to Duke University is to fly which takes 5h 42m and costs $130 - $600.
The distance between Knoxville and Duke University is 324 miles. The road distance is 318.2 miles.
It takes approximately 5h 42m to get from Knoxville to Duke University, including transfers.
Yes, the driving distance between Knoxville to Duke University is 318 miles. It takes approximately 6h 15m to drive from Knoxville to Duke University.
There are 386+ hotels available in Duke University.
What companies run services between Knoxville, TN, USA and Duke University, NC, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU) hourly.
- Website
- delta.com
Flights from Mcghee Tyson Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $100–550
- Website
- aa.com
Flights from Mcghee Tyson Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $75–480
Flights from Mcghee Tyson Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $110–600
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 22m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Mcghee Tyson Airport to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 4h 35m
- When
- Saturday
- Estimated price
- $120–650
- Website
- united.com
Flights from Mcghee Tyson Airport to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charlotte Amtrak Station to Durham Amtrak Station
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Estimated price
- $45–100
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-423-725-5988
- Website
- blackbearresorttn.com
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
- Phone
- +1 828-327-2340
- [email protected]
- Website
- hickoryhop.com
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- hickoryhop.com
Bus from Blowing Rock - Tanger Outlets to Hickory Airport
- Ave. Duration
- 59 min
- Frequency
- Every 4 hours
- Estimated price
- $30–45
- Schedules at
- hickoryhop.com
- Phone
- +1 617-681-0820
- [email protected]
- Website
- coachrun.com
Bus from Charlotte, NC - 3302 Queen City Dr to Durham, NC - 3446 Hillsborough Rd
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a week
- Estimated price
- $12–40
- Website
- https://www.coachrun.com
- Ave. Duration
- 1h 12m
- Estimated price
- $120–170
Reliable Taxi
- Phone
- +1-423-426-6003
Yellow Cab
- Phone
- +1-828-322-1133
Want to know more about travelling around United States
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