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How to get fromKnoxville to Durhamby plane, car, shuttle, taxi, bus, or train

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There are 4 ways to get from Knoxville to Durham by plane, car, shuttle, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU)plane plane TYS - RDU
    5h 6m
    $133–533

  2. Drive 322 mi

    cheapest
    1. Drive from Knoxville to Durhamcar car 322 mi
    6h 8m
    $59–85

  3. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Blowing Rock - Tanger Outletstaxi taxi
    4. Take the bus from Blowing Rock - Tanger Outlets to Hickory Airportbus bus
    5. Take the bus from Hickory Airport to Charlotte Airportbus bus
    6. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    12h 43m
    $415–531

  4. Drive, shuttle, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus bus
    5. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    12h 53m
    $369–447

Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU) flights

Calendar118Weekly Planes
Duration4h 10mAverage Duration
Ticket$70Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Durham.ExpandLaunch map view
  • Distance: 320.4 mi
  • Duration: 5h 6m

What companies run services between Knoxville, TN, USA and Durham, NC, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU) hourly.

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