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How to get fromKnoxville to Floridaby plane, bus (Greyhound, Flixbus), car, shuttle, taxi, bus, or train

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There are 11 ways to get from Knoxville to Florida by plane, bus (Greyhound, Flixbus), car, shuttle, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Jacksonville

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Jacksonville (JAX)plane plane TYS - JAX
    3h 18m
    $128–540

  2. Drive  507.2 mi

    cheapest
    1. Drive from Knoxville to Jacksonvillecar car 507.2 mi
    9h 40m
    $93–134

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    17h 20m
    $224–327

  4. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Boonetaxi taxi
    4. Take the bus from Boone to Forsyth Hospitalbus bus
    5. Take the train from High Point to Carytrain train
    6. Take the train from Cary to Jacksonvilletrain train
    23h 21m
    $427–660

  5. Fly to Orlando Sanford

    1. Fly from Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB)plane plane TYS - SFB
    2h 24m
    $187–572

  6. Fly to Fort Lauderdale–Hollywood International Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TYS - FLL
    2h 58m
    $154–620

  7. Fly to Miami International Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Miami International Airport (MIA)plane plane TYS - MIA
    2h 59m
    $150–560

  8. Fly to Orlando

    1. Fly from Mcghee Tyson Airport (TYS) to Orlando (MCO)plane plane TYS - MCO
    3h 24m
    $141–542

  9. Fly to Saint Petersburg–Clearwater International Airport, line 11 bus

    1. Fly from Mcghee Tyson Airport (TYS) to Saint Petersburg–Clearwater International Airport (PIE)plane plane TYS - PIE
    2. Take the bus from Psta 34Th St Layby - Platform - B to Grand Central Station - Abus bus
    3h 50m
    $138–513

  10. Drive, shuttle, taxi, bus

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Boonetaxi taxi
    4. Take the bus from Boone to Charlottebus bus
    5. Take the bus from Charlotte Bus Station to Jacksonvillebus bus
    18h 16m
    $343–428

  11. Bus via Clarksville Exit 11 Park And Ride

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    20h 25m
    $229–337

Mcghee Tyson Airport (TYS) to Jacksonville (JAX) flights

Calendar43Weekly Planes
Duration2h 56mAverage Duration
Ticket$74Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Florida.ExpandLaunch map view
  • Distance: 420.9 mi
  • Duration: 3h 18m

What companies run services between Knoxville, TN, USA and Florida, USA?

Allegiant Air and Delta fly from Mcghee Tyson Airport (TYS) to Jacksonville (JAX) every 4 hours. Alternatively, you can take a vehicle from Knoxville to Newnan St + Ashley St via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Atlanta Bus Station, Jacksonville, and JRTC Bay J in around 17h 20m.

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