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How to get fromKnoxville to Fort Pierceby plane, car, bus (Flixbus, Greyhound), bus, train, or shuttle

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There are 8 ways to get from Knoxville to Fort Pierce by plane, car, bus (Flixbus, Greyhound), bus, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Melbourne International Airport, drive

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Melbourne International Airport (MLB)plane plane TYS - MLB
    2. Drive from Melbourne International Airport (MLB) to Fort Piercecar car
    4h 46m
    $157–582

  2. Drive 742.8 mi

    cheapest
    1. Drive from Knoxville to Fort Piercecar car 742.8 mi
    12h 30m
    $136–196

  3. Bus

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the bus from New York City Chinatown to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Fort Piercebus bus
    41h 48m
    $313–474

  4. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from Ny Moynihan Train Hall At Penn Station to West Palm Beach Amtrak Stationtrain train
    3. Take the bus from West Palm Beach, FL to Fort Piercebus bus
    42h 26m
    $605–1,122

  5. Fly to Orlando Sanford, drive

    1. Fly from Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB)plane plane TYS - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Fort Piercecar car
    4h 10m
    $159–572

  6. Fly to Orlando, shuttle

    1. Fly from Mcghee Tyson Airport (TYS) to Orlando (MCO)plane plane TYS - MCO
    2. Take a shuttle bus from Orlando Airport to Fort Pierce, FL - Dunkin' Donutsshuttle bus
    5h
    $233–644

  7. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TYS - FLL
    2. Take the bus from Fort Lauderdale Airport to Fort Piercebus bus
    5h 28m
    $209–700

  8. Fly to Miami International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Miami International Airport (MIA)plane plane TYS - MIA
    2. Take the bus from Miami Airport to Fort Piercebus bus
    6h 8m
    $209–660

Mcghee Tyson Airport (TYS) to Melbourne International Airport (MLB) flights

Calendar28Weekly Planes
Duration4h 14mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Fort Pierce.ExpandLaunch map view
  • Distance: 634.8 mi
  • Duration: 4h 46m

What companies run services between Knoxville, TN, USA and Fort Pierce, FL, USA?

You can take a bus from Knoxville Station Bay H to Fort Pierce via Fountain City Superstop, Walmart, Knoxville, TN, New York City Chinatown, Orlando Bus Station, and Fort Pierce in around 41h 48m.

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