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How to get fromKnoxville to Fort Wayneby plane, bus (Greyhound, Amtrak), car, or bus (Greyhound)

Find Transport to Fort Wayne

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There are 4 ways to get from Knoxville to Fort Wayne by plane, bus (Greyhound, Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Fort Wayne International Airport (FWA)plane plane TYS - FWA
    4h 41m
    $187–612

  2. Drive 404.1 mi

    cheapest
    1. Drive from Knoxville to Fort Waynecar car 404.1 mi
    8h 2m
    $74–107

  3. Bus via Indianapolis

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis, IN to Fort Wayne, INbus bus
    14h 41m
    $192–326

  4. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Ft Wayne Citilink Central Stationbus bus Greyhound US0112
    15h 38m
    $205–311

Mcghee Tyson Airport (TYS) to Fort Wayne International Airport (FWA) flights

Calendar81Weekly Planes
Duration5h 16mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Fort Wayne.ExpandLaunch map view
  • Distance: 388.6 mi
  • Duration: 4h 41m

What companies run services between Knoxville, TN, USA and Fort Wayne, IN, USA?

Delta, United Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Fort Wayne International Airport (FWA) every 2 hours. Alternatively, you can take a vehicle from Knoxville to Glenbrook Square via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Indianapolis, IN, Fort Wayne, IN, and Central Station - Bay A in around 14h 41m.

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