Rome2Rio

How to get fromKnoxville to Frederickby plane, bus, car, shuttle, taxi, train, or bus (Greyhound)

Find Transport to Frederick

See all options

There are 6 ways to get from Knoxville to Frederick by plane, bus, car, shuttle, taxi, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Baltimore-Washington International Airport, bus

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Baltimore-Washington International Airport (BWI)plane plane TYS - BWI
    2. Take the bus from Baltimore Airport to Frederick Bus Stationbus bus
    4h 12m
    $227–757

  2. Drive 473.4 mi

    cheapest
    1. Drive from Knoxville to Frederickcar car 473.4 mi
    7h 54m
    $87–125

  3. Drive, shuttle, taxi, bus, train

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Bristol Exit 5 Park & Ride Lot to Washington Union Stationbus bus
    5. Take the train from Washington Union Station to FREDERICK MARC wbtrain train
    16h 9m
    $297–353

  4. Fly to Ronald Reagan Washington National Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Ronald Reagan Washington National Airport (DCA)plane plane TYS - DCA
    2. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus
    4h 46m
    $183–776

  5. Fly to Washington Dulles International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Washington Dulles International Airport (IAD)plane plane TYS - IAD
    2. Take the bus from Market St & Harrison St to Frederick Transit Stationbus bus
    4h 48m
    $136–542

  6. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Frederick Bus Stationbus bus
    22h 4m
    $240–383

Mcghee Tyson Airport (TYS) to Baltimore-Washington International Airport (BWI) flights

Calendar46Weekly Planes
Duration3h 22mAverage Duration
Ticket$105Cheapest Price
See schedules

Questions & Answers

Map of how to get from Knoxville to Frederick.ExpandLaunch map view
  • Distance: 526.4 mi
  • Duration: 4h 12m

What companies run services between Knoxville, TN, USA and Frederick, MD, USA?

You can take a vehicle from Knoxville to Frederick Bus Station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, and Washington Union Station in around 22h 4m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound