Rome2Rio

How to get fromKnoxville to Greenvilleby plane, taxi, bus, train, or car

Find Transport to Greenville

See all options

There are 8 ways to get from Knoxville to Greenville by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Monroe Regional Airport, taxi

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Monroe Regional Airport (MLU)plane plane TYS - MLU
    2. Take the taxi from Monroe Regional Airport (MLU) to Greenvilletaxi taxi
    6h 32m
    $174–643

  2. Drive 533.3 mi

    cheapest
    1. Drive from Knoxville to Greenvillecar car 533.3 mi
    9h 12m
    $98–141

  3. Bus, train, drive

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Jacksonbus bus
    3. Take the train from Jackson to Yazoo City Amtrak Stationtrain train
    4. Drive from Yazoo City Amtrak Station to Greenvillecar car
    17h 48m
    $202–296

  4. Fly Mcghee Tyson Airport to Greenville International Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Greenville International Airport (GLH)plane plane TYS - GLH
    4h 37m
    $219–793

  5. Fly Mcghee Tyson Airport to Jackson/Vicksburg, train, drive

    1. Fly from Mcghee Tyson Airport (TYS) to Jackson/Vicksburg (JAN)plane plane TYS - JAN
    2. Take the train from Jackson to Yazoo City Amtrak Stationtrain train
    3. Drive from Yazoo City Amtrak Station to Greenvillecar car
    7h 10m
    $209–657

  6. Drive to Chattanooga Metropolitan Airport, fly to Greenville International Airport

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Greenville International Airport (GLH)plane plane CHA - GLH
    6h 9m
    $136–523

  7. Drive to Asheville Regional Airport, fly to Greenville International Airport

    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Greenville International Airport (GLH)plane plane AVL - GLH
    5h 51m
    $144–558

  8. Bus, train, drive via Carbondale

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the train from Carbondale to Greenwood Amtrak Stationtrain train
    4. Drive from Greenwood Amtrak Station to Greenvillecar car
    18h 30m
    $272–469

Mcghee Tyson Airport (TYS) to Monroe Regional Airport (MLU) flights

Calendar45Weekly Planes
Duration5h 3mAverage Duration
Ticket$95Cheapest Price
See schedules

Questions & Answers

Map of how to get from Knoxville to Greenville.ExpandLaunch map view
  • Distance: 626.1 mi
  • Duration: 6h 32m

What companies run services between Knoxville, TN, USA and Greenville, MS, USA?

Delta, Key Lime, and American Airlines fly from Mcghee Tyson Airport (TYS) to Greenville International Airport (GLH) once daily.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound