There are 2 ways to get from Knoxville to Greenville by car or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Mcghee Tyson Airport (TYS) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Knoxville to Greenville is to drive which costs $30 - $45 and takes 3h 7m.
The fastest way to get from Knoxville to Greenville is to drive which takes 3h 7m and costs $30 - $45.
The distance between Knoxville and Greenville is 169 miles. The road distance is 168.9 miles.
It takes approximately 3h 7m to drive 168.9 miles from Knoxville to Greenville.
Yes, the driving distance between Knoxville to Greenville is 169 miles. It takes approximately 3h 7m to drive from Knoxville to Greenville.
There are 268+ hotels available in Greenville.
What companies run services between Knoxville, TN, USA and Greenville, SC, USA?
Delta, Southwest Airlines, and three other airlines fly from Mcghee Tyson Airport (TYS) to Greenville–Spartanburg International Airport (GSP) hourly.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $90–650
- Website
- delta.com
Flights from Mcghee Tyson Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $95–650
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $110–700
- Website
- united.com
Flights from Mcghee Tyson Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $160–850
- Website
- allegiantair.com
Flights from Mcghee Tyson Airport to Greenville–Spartanburg International Airport via Sarasota/Bradenton
- Ave. Duration
- 6h 17m
- When
- Sunday
- Estimated price
- $210–1,000
Flights from Mcghee Tyson Airport to Greenville–Spartanburg International Airport via Orlando Sanford
- Ave. Duration
- 6h 53m
- When
- Thursday
- Estimated price
- $180–950
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