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How to get fromKnoxville to Harrisburg, Paby plane, bus, train, car, or bus (Flixbus)

Find Transport to Harrisburg, Pa

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There are 5 ways to get from Knoxville to Harrisburg, Pa by plane, bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Harrisburg International Airport (MDT)plane plane TYS - MDT
    5h 1m
    $148–569

  2. Drive 536.7 mi

    cheapest
    1. Drive from Knoxville to Harrisburg, Pacar car 536.7 mi
    8h 59m
    $98–142

  3. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Harrisburgtrain train Keystone Service / ...
    17h
    $200–293

  4. Fly to Philadelphia International Airport, train

    1. Fly from Mcghee Tyson Airport (TYS) to Philadelphia International Airport (PHL)plane plane TYS - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    5h 38m
    $220–840

  5. Bus

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the bus from New York City Chinatown to Harrisburg Bus Stationbus bus FlixBus N2640
    21h 4m
    $133–174

Mcghee Tyson Airport (TYS) to Harrisburg International Airport (MDT) flights

Calendar118Weekly Planes
Duration4h 49mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Harrisburg, Pa.ExpandLaunch map view
  • Distance: 519.8 mi
  • Duration: 5h 1m

What companies run services between Knoxville, TN, USA and Harrisburg, Pa, PA, USA?

United Airlines, American Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Harrisburg International Airport (MDT) hourly. Alternatively, you can take a bus from Knoxville Station Bay H to Harrisburg Bus Station via Fountain City Superstop, Walmart, Knoxville, TN, and New York City Chinatown in around 21h 4m.

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