There are 3 ways to get from Knoxville to Hartsville by plane, taxi, car, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, taxi
best- Fly from Mcghee Tyson Airport (TYS) to Florence Regional Airport (FLO)plane TYS - FLO
- Take the taxi from Florence Regional Airport (FLO) to Hartsvilletaxi
4h 29m$202–597Drive 299.5 mi
cheapest- Drive from Knoxville to Hartsvillecar 299.5 mi
6h 13m$55–79Drive, shuttle, bus, taxi
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the taxi from Camden to Hartsvilletaxi
12h 17m$460–530
Mcghee Tyson Airport (TYS) to Florence Regional Airport (FLO) flights
Questions & Answers
The cheapest way to get from Knoxville to Hartsville is to drive which costs $50 - $80 and takes 6h 13m.
The fastest way to get from Knoxville to Hartsville is to fly and taxi which takes 4h 29m and costs $200 - $600.
The distance between Knoxville and Hartsville is 305 miles. The road distance is 301.2 miles.
It takes approximately 4h 29m to get from Knoxville to Hartsville, including transfers.
Yes, the driving distance between Knoxville to Hartsville is 301 miles. It takes approximately 6h 13m to drive from Knoxville to Hartsville.
There are seven+ hotels available in Hartsville.
What companies run services between Knoxville, TN, USA and Hartsville, SC, USA?
There is no direct connection from Knoxville to Hartsville. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Florence Regional Airport (FLO), then take the taxi to Hartsville. Alternatively, you can drive to Hot Springs, take the shuttle to Black Bear Resort, take the shuttle to Boone, walk to ASU Peacock Hall Boone, take the bus to Charlotte Airport, walk to Charlotte Douglas Airport, take the line 5 bus to Transit Center- Bay V, walk to Transit Center- Bay E, take the line 34 bus to 4th St & Graham St, walk to Charlotte Bus Station, take the bus to Camden, then take the taxi to Hartsville.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $65–430
- Phone
- +1-423-725-5988
- Website
- blackbearresorttn.com
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
- Phone
- +1 828-327-2340
- [email protected]
- Website
- hickoryhop.com
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- hickoryhop.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
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