There are 5 ways to get from Knoxville to Houston by plane, bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Mcghee Tyson Airport to William P. Hobby Airport
best- Fly from Mcghee Tyson Airport (TYS) to William P. Hobby Airport (HOU)plane TYS - HOU
3h 29m$134–479Drive to Chattanooga Metropolitan Airport, fly to George Bush Intercontinental Airport
cheapest- Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car
- Fly from Chattanooga Metropolitan Airport (CHA) to George Bush Intercontinental Airport (IAH)plane CHA - IAH
5h 26m$100–479Bus
- Take the bus from Knoxville to Memphis - Summer Avebus Nyc
- Take the bus from Memphis Bus Station to Downtown Houstonbus FlixBus N2211
25h 28m$265–376Drive 898.7 mi
- Drive from Knoxville to Houstoncar 898.7 mi
15h 37m$154–222Fly Mcghee Tyson Airport to George Bush Intercontinental Airport
- Fly from Mcghee Tyson Airport (TYS) to George Bush Intercontinental Airport (IAH)plane TYS - IAH
4h$144–541
Mcghee Tyson Airport (TYS) to William P. Hobby Airport (HOU) flights
Comparing Your Travel Options
The cheapest way to get from Knoxville to Houston is to drive which costs $150 - $230 and takes 15h 37m.
The fastest way to get from Knoxville to Houston is to fly which takes 3h 29m and costs $130 - $480.
No, there is no direct bus from Knoxville to Houston. However, there are services departing from Knoxville and arriving at Downtown Houston via SUMMER AVENUE at WHITE STATION ROAD, William Hudson Transit Center and Memphis Bus Station. The journey, including transfers, takes approximately 25h 28m.
The distance between Knoxville and Houston is 807 miles. The road distance is 903.9 miles.
The best way to get from Knoxville to Houston without a car is to bus which takes 25h 28m and costs $260 - $380.
It takes approximately 3h 29m to get from Knoxville to Houston, including transfers.
Knoxville to Houston bus services, operated by Wanda Coach, depart from Knoxville station.
The best way to get from Knoxville to Houston is to fly which takes 3h 29m and costs $130 - $480. Alternatively, you can bus, which costs $260 - $380 and takes 25h 28m.
Knoxville to Houston bus services, operated by Wanda Coach, arrive at Memphis - Summer Ave station.
Houston is 1h behind Knoxville. It is currently 7:20 PM in Knoxville and 6:20 PM in Houston.
What companies run services between Knoxville, TN, USA and Houston, TX, USA?
Allegiant Air, Delta, and Southwest Airlines fly from Mcghee Tyson Airport (TYS) to William P. Hobby Airport (HOU) every 4 hours. Alternatively, you can take a vehicle from Knoxville to Downtown Houston via Knoxville, Memphis - Summer Ave, SUMMER AVENUE at WHITE STATION ROAD, William Hudson Transit Center, AIRWAYS BOULEVARD at BROOKS ROAD, and Memphis Bus Station in around 25h 28m.
- Website
- delta.com
Flights from Mcghee Tyson Airport to William P. Hobby Airport via Atlanta
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $80–420
Flights from Mcghee Tyson Airport to George Bush Intercontinental Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $90–480
Flights from Chattanooga Metropolitan Airport to George Bush Intercontinental Airport via Atlanta
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $90–470
- Website
- aa.com
Flights from Mcghee Tyson Airport to George Bush Intercontinental Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $100–550
Flights from Chattanooga Metropolitan Airport to George Bush Intercontinental Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $95–500
Flights from Chattanooga Metropolitan Airport to George Bush Intercontinental Airport via Charlotte
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $110–550
- Website
- united.com
Flights from Mcghee Tyson Airport to George Bush Intercontinental Airport
- Ave. Duration
- 2h 38m
- When
- Every day
- Estimated price
- $85–470
Flights from Chattanooga Metropolitan Airport to George Bush Intercontinental Airport
- Ave. Duration
- 2h 34m
- When
- Every day
- Estimated price
- $80–450
Flights from Chattanooga Metropolitan Airport to George Bush Intercontinental Airport via Chicago O'Hare
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $130–600
- Website
- southwest.com
Flights from Mcghee Tyson Airport to William P. Hobby Airport via Dallas
- Ave. Duration
- 4h 55m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–450
Flights from Mcghee Tyson Airport to William P. Hobby Airport via Nashville
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $80–420
Flights from Mcghee Tyson Airport to William P. Hobby Airport via Austin
- Ave. Duration
- 5h 10m
- When
- Friday
- Estimated price
- $90–460
- Website
- allegiantair.com
Flights from Mcghee Tyson Airport to William P. Hobby Airport
- Ave. Duration
- 2h 20m
- When
- Friday and Monday
- Estimated price
- $75–410
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Knoxville to Memphis - Summer Ave
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $55–80
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $55–80
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Memphis Bus Station to Downtown Houston
- Ave. Duration
- 14h 25m
- Frequency
- 5 times a week
- Estimated price
- $120–190
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Knoxville to Houston is 904 miles. It takes approximately 15h 37m to drive from Knoxville to Houston.
There are 2184+ hotels available in Houston.

