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How to get fromKnoxville to Houstonby plane, bus (Flixbus), or car

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There are 5 ways to get from Knoxville to Houston by plane, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to William P. Hobby Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to William P. Hobby Airport (HOU)plane plane TYS - HOU
    3h 26m
    $149–559

  2. Drive to Chattanooga Metropolitan Airport, fly to George Bush Intercontinental Airport

    cheapest
    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to George Bush Intercontinental Airport (IAH)plane plane CHA - IAH
    5h 12m
    $106–491

  3. Bus

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Downtown Houstonbus bus FlixBus N2211
    25h 13m
    $255–366

  4. Drive  898.7 mi

    1. Drive from Knoxville to Houstoncar car 898.7 mi
    15h 42m
    $164–237

  5. Fly Mcghee Tyson Airport to George Bush Intercontinental Airport

    1. Fly from Mcghee Tyson Airport (TYS) to George Bush Intercontinental Airport (IAH)plane plane TYS - IAH
    3h 53m
    $159–671

Mcghee Tyson Airport (TYS) to William P. Hobby Airport (HOU) flights

Calendar42Weekly Planes
Duration4h 14mAverage Duration
Ticket$94Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Houston.ExpandLaunch map view
  • Distance: 802.5 mi
  • Duration: 3h 26m

What companies run services between Knoxville, TN, USA and Houston, TX, USA?

Allegiant Air, Southwest Airlines, and Delta fly from Mcghee Tyson Airport (TYS) to William P. Hobby Airport (HOU) every 4 hours. Alternatively, you can take a vehicle from Knoxville to Downtown Houston via Knoxville, Memphis - Summer Ave, SUMMER AVENUE at WHITE STATION ROAD, William Hudson Transit Center, AIRWAYS BOULEVARD at BROOKS ROAD, and Memphis Bus Station in around 25h 13m.

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