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How to get fromKnoxville to Indianaby plane, bus (Greyhound, Amtrak), car, train, or bus (Flixbus)

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There are 6 ways to get from Knoxville to Indiana by plane, bus (Greyhound, Amtrak), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Evansville

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Evansville (EVV)plane plane TYS - EVV
    3h 49m
    $156–560

  2. Drive 347.6 mi

    cheapest
    1. Drive from Knoxville to Indianapoliscar car 347.6 mi
    6h 1m
    $64–92

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    10h 49m
    $178–224

  4. Fly to Chicago O'Hare International Airport, train

    1. Fly from Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD)plane plane TYS - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    4h 17m
    $131–451

  5. Fly to Chicago Midway International Airport, train

    1. Fly from Mcghee Tyson Airport (TYS) to Chicago Midway International Airport (MDW)plane plane TYS - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    3h 51m
    $141–521

  6. Bus via Indianapolis

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Indianapolisbus bus FlixBus 2512
    11h 49m
    $183–254

Mcghee Tyson Airport (TYS) to Evansville (EVV) flights

Calendar72Weekly Planes
Duration5h 2mAverage Duration
Ticket$83Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Indiana.ExpandLaunch map view
  • Distance: 268.8 mi
  • Duration: 3h 49m

What companies run services between Knoxville, TN, USA and Indiana, USA?

Delta, American Airlines, and Allegiant Air fly from Mcghee Tyson Airport (TYS) to Evansville (EVV) every 3 hours. Alternatively, you can take a vehicle from Knoxville to Indianapolis Union Station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, and Nashville Bus Station in around 10h 49m.

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