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How to get fromKnoxville to Iowa Cityby plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Flixbus)

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There are 6 ways to get from Knoxville to Iowa City by plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to The Eastern Iowa Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to The Eastern Iowa Airport (CID)plane plane TYS - CID
    5h 58m
    $157–617

  2. Drive 704.1 mi

    cheapest
    1. Drive from Knoxville to Iowa Citycar car 704.1 mi
    12h 10m
    $129–186

  3. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville to Chicago Union Stationbus bus
    3. Take the train from Chicago Union Station to Napervilletrain train
    4. Take the bus from Naperville to Iowa Citybus bus
    21h 13m

  4. Fly to Quad City International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Quad City International Airport (MLI)plane plane TYS - MLI
    2. Take the bus from Moline Center Station to Iowa Citybus bus
    7h 56m
    $162–636

  5. Bus via Indianapolis

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis to Chicago Bus Stationbus bus
    4. Take the bus from Chicago to Iowa Citybus bus
    26h

  6. Bus

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago to Iowa Citybus bus
    26h 18m
    $265–426

Mcghee Tyson Airport (TYS) to The Eastern Iowa Airport (CID) flights

Calendar75Weekly Planes
Duration5h 32mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Iowa City.ExpandLaunch map view
  • Distance: 625.8 mi
  • Duration: 5h 58m

What companies run services between Knoxville, TN, USA and Iowa City, IA, USA?

United Airlines, American Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to The Eastern Iowa Airport (CID) every 2 hours. Alternatively, you can take a vehicle from Knoxville to Iowa City via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Indianapolis, Lafayette Rd & Office Plaza Blvd, Ctc-R, Indianapolis, and Chicago in around 26h.

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