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How to get fromKnoxville to Islipby plane, train, bus, or car

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There are 7 ways to get from Knoxville to Islip by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Laguardia Airport, train

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Laguardia Airport (LGA)plane plane TYS - LGA
    2. Take the train from Jamaica to Isliptrain train
    4h 50m
    $165–641

  2. Drive  738.2 mi

    cheapest
    1. Drive from Knoxville to Islipcar car 738.2 mi
    13h 23m
    $127–183

  3. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from Jamaica to Isliptrain train Montauk Branch
    15h
    $150–184

  4. Fly Mcghee Tyson Airport to Long Island Mac Arthur Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Long Island Mac Arthur Airport (ISP)plane plane TYS - ISP
    5h 59m
    $133–483

  5. Fly Mcghee Tyson Airport to Newark Liberty International Airport, train

    1. Fly from Mcghee Tyson Airport (TYS) to Newark Liberty International Airport (EWR)plane plane TYS - EWR
    2. Take the train from New York Penn Station to Babylontrain train
    5h 2m
    $146–444

  6. Drive to Asheville Regional Airport, fly to Laguardia Airport, train

    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Laguardia Airport (LGA)plane plane AVL - LGA
    3. Take the train from Jamaica to Isliptrain train
    6h 37m
    $129–604

  7. Fly Mcghee Tyson Airport to Philadelphia International Airport, train

    1. Fly from Mcghee Tyson Airport (TYS) to Philadelphia International Airport (PHL)plane plane TYS - PHL
    2. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from New York Penn Station to Babylontrain train
    6h 32m
    $166–1,139

Mcghee Tyson Airport (TYS) to Laguardia Airport (LGA) flights

Calendar82Weekly Planes
Duration3h 32mAverage Duration
Ticket$98Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Islip.ExpandLaunch map view
  • Distance: 701 mi
  • Duration: 4h 50m

What companies run services between Knoxville, TN, USA and Islip, NY, USA?

Southwest Airlines, Allegiant Air, and two other airlines fly from Mcghee Tyson Airport (TYS) to Long Island Mac Arthur Airport (ISP) twice daily.

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