Rome2Rio

How to get fromKnoxville to Jacksonville (Station)by plane, bus, bus (Greyhound, Flixbus), or car

Find Transport to Jacksonville (Station)

See all options

There are 5 ways to get from Knoxville to Jacksonville (Station) by plane, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Jacksonville, line 4 bus

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Jacksonville (JAX)plane plane TYS - JAX
    2. Take the bus from JRTC Bay H to Amtrak Stationbus bus
    4h 3m
    $144–623

  2. Drive 502.6 mi

    cheapest
    1. Drive from Knoxville to Jacksonville (Station)car car 502.6 mi
    9h 31m
    $92–133

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    17h 29m
    $224–352

  4. Fly to Orlando Sanford, drive

    1. Fly from Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB)plane plane TYS - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Jacksonville (Station)car car
    4h 21m
    $170–602

  5. Bus via Clarksville Exit 11 Park And Ride

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    20h 56m
    $229–367

Mcghee Tyson Airport (TYS) to Jacksonville (JAX) flights

Calendar15Weekly Planes
Duration2h 54mAverage Duration
Ticket$88Cheapest Price
See schedules

Questions & Answers

Map of how to get from Knoxville to Jacksonville (Station).ExpandLaunch map view
  • Distance: 428 mi
  • Duration: 4h 3m

What companies run services between Knoxville, TN, USA and Jacksonville (Station), FL, USA?

You can take a vehicle from Knoxville to Amtrak Station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Atlanta Bus Station, Jacksonville, and JRTC Bay H in around 17h 29m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound