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How to get fromKnoxville to Kansas Cityby plane, bus (Greyhound, Flixbus), car, bus, or train

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There are 6 ways to get from Knoxville to Kansas City by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Kansas City (MCI)plane plane TYS - MCI
    5h 45m
    $217–917

  2. Drive 727.7 mi

    cheapest
    1. Drive from Knoxville to Kansas Citycar car 727.7 mi
    12h 8m
    $133–192

  3. Bus via St. Louis

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    17h 15m
    $208–329

  4. Drive to Chattanooga Metropolitan Airport, fly

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Kansas City (MCI)plane plane CHA - MCI
    7h 53m
    $229–1,127

  5. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to St Louis Bus Stationbus bus
    4. Take the train from St. Louis to Kansas Citytrain train
    18h 55m
    $263–444

  6. Bus

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Kansas Citybus bus Jefferson 120
    20h 48m
    $255–346

Mcghee Tyson Airport (TYS) to Kansas City (MCI) flights

Calendar102Weekly Planes
Duration5h 31mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Kansas City.ExpandLaunch map view
  • Distance: 670.5 mi
  • Duration: 5h 45m

What companies run services between Knoxville, TN, USA and Kansas City, MO, USA?

Southwest Airlines, Delta, and two other airlines fly from Mcghee Tyson Airport (TYS) to Kansas City (MCI) hourly. Alternatively, you can take a vehicle from Knoxville to Kansas City Bus Station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 5Th Ave - Bay 11, Clarksville Exit 11 Park And Ride, Clarksville Park & Ride, and St Louis Bus Station in around 17h 15m.

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